PSI2020 - Save the Date

[Jones, Andy]

Hi all,

 

We are pleased to announce that the 2020 Annual workshop for the Proteomics Standards Initiative (PSI) will take place in San Diego USA, Mon 23^rd to Thurs 26^th March 2020. The workshop will focus on developing data standards related to mass spectrometry for spectral libraries, the universal spectrum identifier, quality control and capturing study metadata, and in the molecular interactions side on mapping standards to Cytoscape. We will also be welcoming the new PSI work group – Intrinsically Disordered Proteins (IDP).

 

Please save the date if you might be interested to attend, we are always pleased to welcome new groups into the PSI. The registration page will be made available in the coming weeks.

 

Best wishes

Andy Jones on behalf of the PSI steering committee

 

[Zaia, Joseph]

Dear All,

 

I would like to initiate discussion for expanding the use cases for proteomics to include complex protein glycosylation.  Glycosylation is as a rule heterogeneous, with 30 or so glycoforms per glycosite.  In addition, the glycan dissociates during tandem MS experiments.  The software and data standards need to be expanded to include the glycosylation size, heterogeneity, and tandem MS dissociation.  At present, quantitative software (Skyline and others) do not recognize glycosylation.  Without this recognition the quantitative tools developed for peptides cannot be adapted without tedious effort on the part of the user.  Therefore, there is need to expand the manner by which peptides are represented informatically.  It is important that glycopeptides be included in the use cases for mzIdentML and mzQuant.  It is also important that spectral library generating software be expanded to allow glycosylated peptides to facilitate use of data independent experiments for glycoproteins.

 

Would it be possible for me to communicate these ideas at the PSI Workshop in San Diego? 

 

Thank you.

 

Joe Zaia

[Juan Antonio Vizcaino]

Dear Joe,

Thanks for your e-mail.

You are very welcome to present in San Diego. We are still discussing the agenda, but we will make sure you get a slot.

Best regards,

Juan

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[Zaia, Joseph]

Thanks, Juan. I look forward to attending the spring HUPO-PSI meeting.

 

Joe

[Robert Chalkley]

I would also be keen to be involved in discussions about supporting glycopeptide data.

Robert

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Robert Chalkley PhD
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[Eric Deutsch]

Hi Robert, great, thanks for contributing! We will try to schedule a specific session for this and announce it so that everyone knows when it is in advance.

 

Thanks,

Eric

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[Zaia, Joseph]

I have been in touch with Nathan Edwards (Georgetown University, copied).  He expressed interest in attending the session to discuss supporting glycoproteomics data. 

 

Best regards,

 

Joe

[Eric Deutsch]

Thanks, Joe, it looks like there is great interest. We have a workshop planning call next week and will create a slot for a session on this. The dates for the workshop are:

 

Mon Mar 23:

Tue Mar 24:

Wed Mar 25:

Thu Mar 26:

 

If anyone very interested in a glycoproteomics session has any major constraints in participation on these days, please let me know and we can try to work around it to maximize participation.

 

Thanks,

Eric