cbioportal

[sabire kılıçarslan]

Dear cBioPortal Team,

I hope this message finds you well.

I am interested in performing a differential gene expression (DEG) analysis using the expression data available on cBioPortal, specifically the "mRNA Expression z‑Scores (RNA Seq V2 RSEM)" dataset.

However, I would like to ask which type of expression data you recommend using for meaningful and statistically sound DEG analysis. For instance, would z-scores, RSEM-normalized expression values, or raw counts be more appropriate for this purpose?

I would greatly appreciate your guidance on which dataset to use and any suggestions you may have regarding best practices for DEG analysis using cBioPortal data.

Thank you very much for your time and support.

[Nikolaus Schultz]

Dear Sabire,

The RSEM-normalized expression values would probably be best for your purpose.

Niki.

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[sabire kılıçarslan]

Thank you

24 Haz 2025 Sal 22:40 tarihinde Nikolaus Schultz <nsch...@gmail.com> şunu yazdı: