HI Nitin,
Yes, you can do that with a web application. Angular is well suited for this, and is well tested for memory degradation.
But it's easy to make something that leaks memory, so you need to profile it thoroughly.
Also, I assume it's running in some kind of browser environment. Those things are usually leaking more memory as web-apps themselves. So a daily automated restart might save you a lot of headaches.
Regards
Sander