On Tuesday, August 16, 2016 at 9:46:49 PM UTC-4, Öö Tiib wrote:
> On Wednesday, 17 August 2016 00:51:50 UTC+3, Peter Nyikos wrote:
> > On Tuesday, August 16, 2016 at 8:41:51 AM UTC-4, Öö Tiib wrote:
This is the third and final reply to your thought-provoking post.
> > > I do not understand neither side in this discussion. Both sides seem
> > > to implicitly agree that last mutation that resulted with flagellum had
> > > to be one that added some part to it.
> >
> > I never went down that path, because "that last mutation" might have
> > just rendered a previously redundant part indispensible. There are
> > other alternatives, as you know:
> >
> > > Eddie demands that predecessor
> > > (without part) had motility for Roger some other function (T3SS) is fine.
> > > To me however that last mutation did not apparently add a part.
> >
> > So you think it removed a part? What might that part have been doing there?
>
> My opinion likely does not matter but about that Salmonella that
> Behe investigated I already speculated.
I missed that. Could you give me a synopsis and/or a link?
> On general case the flagella are quite diverse. Different bacterial
> species have documented from 27 to 80 genes that deal with flagellum.
"deal with flagellum" does not mean the same thing as "produce, via
replication and translation, the various component parts of the flagellum."
Did you actually mean the latter statement?
Even if you did, there may be some ambiguity in just "the flagellum"
to account for some variation. I have seen at least one person include,
in "the flagellum," whatever triggers the secretion that causes the
rotor to rotate and thus cause the long strand of flagellin to propel
the bacterium.
Other variations can be accounted for by what I said earlier:
once an IC system exists, there is nothing to rule out it evolving into
another system.
In fact, this is what probably happened with the bacterial
flagellum. Originating in gram-negative bacteria, it shed two
rings as the bacterium evolved into a gram-positive bacterium,
which had one less outer layer and so did not need the shed rings.
There may have been other changes along such unexceptional lines,
accounting for the unspecified "thousands of variations"
that have been alleged by Steady Eddie.
> Not all bacteria are well studied because scientists are most interested
> in parasites of human and in bacteria used in food industry (for obvious
> reasons). Most scientists are also uninterested in that IC and ID. The
> few that are interested in do not seemingly do much experiments.
And yet, you would expect Behe's critics to conduct experiments testing
whether the structures Behe claims to be IC aren't really IC. The only
such experiments of which I know were conducted by Minnich and his students,
and they showed that at least one form of the flagellum is IC.
Why didn't they test more of them? you might ask. The "obvious reasons"
about which you speak include: 1. grant money and 2. publishability.
Those knockout experiments might have been fine for Ph.D. dissertations,
but the source of grant money for Minnich's lab had to do with
parasites, for obvious reasons.
> Therefore it can easily be that different species are in different
> stages and that some have IC and some have not IC flagella.
All the more reason, then, for Behe's critics to conduct further
experiments. Instead, they are taking the path of least
resistance, pretending that the evolution of the flagellum has
been adequately accounted for.
> Since
> Salmonella is whole genus it can even be so about different Salmonella.
> IOW we lack experimental data there.
We have some, and the following excerpt from a webpage on a Nobel Laureate
alludes to one set of them:
Arber's findings have been confirmed by many other scientists,
such as Bullas et al. [5]
[5] Bullas, L. R., C. Colson, and A. Van Pel. 1976. DNA restriction and
modification systems in Salmonella. SQ, a new system derived by
recombination between the SB system of Salmonella typhimurium and
the SP system of Salmonella Potsdam.
Journal of General Microbiology. 95 (1): 166-172.
This being a creationist website, you might find some distortions of
what's in the above article. The webpage then drops a clue as to what
Behe's "precipitous drop" may be about:
The most recent replication is by Lenski et al,
who evaluated the changes in over 30,000 generations of E. coli,
concluding that millions of mutations and trillions of cells
were needed to produce the estimated two to three mutations
required to allow cells to bring citrate into the cell under oxic
conditions. [6] This corresponds with Michael Behe's deductions that
if one mutation is required to confer some advantage to an organism,
this event is likely; if two are required, the likelihood is far
less; but if three or more are required, the probability rapidly
grows exponentially worse, from very improbable to impossible.
Evolution by mutations for this reason has very clear limits. [7]
[6] Blount, Z., C. Borland, and R. Lenski. 2008. Historical Contingency
and the Evolution of a Key Innovation in an Experimental Population
of Escherichia coli.
Proceedings of the National Academy of Science. 105: 7899-7906.
[7] Behe, Michael. 2007. The Edge of Evolution. New York: The Free Press.
http://www.icr.org/article/werner-arber-nobel-laureate-darwin-skeptic/
Peter Nyikos
Professor, Department of Math. -- standard disclaimer --
University of South Carolina