[rael-science] War on superbugs could end soon thanks to this new scientific breakthrough
12 views
Skip to first unread message
selected by Rael
unread,
Jan 23, 2017, 5:51:06 AM1/23/17
Reply to author
Sign in to reply to author
Forward
Sign in to forward
Delete
You do not have permission to delete messages in this group
Copy link
Report message
Sign in to report message
Show original message
Either email addresses are anonymous for this group or you need the view member email addresses permission to view the original message
to rael-s...@googlegroups.com
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The Raelian Movement
for those who are not afraid of the future : http://www.rael.org
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Get Rael-Science on Facebook: http://www.facebook.com/raelscience
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Scientists have developed a new weapon in the fight against
superbugs resistant to antibiotics - a breakthrough molecule
that reverses antibiotic resistance in multiple strains of
bacteria.
Oregon State University researchers worked
with international colleagues to create a molecule that can
offset superbugs’ ability to destroy antibiotics.
The major development follows the death of
a Nevada woman last year when a superbug she contracted in India
proved resistant to all 26 antibiotics available in the US.
The Center for Disease Control and
Prevention (CDC) confirmed the death earlier this month.
“The isolate was sent to the CDC for
testing to determine the mechanism of antimicrobial
resistance…[and] confirmed the presence of New Delhi
metallo-beta-lactamase (NDM),” it said.
The agency has highlighted antimicrobial
resistance as “one of the most serious health threats”
currently facing the United States.
This latest study, published in the Journal
of Antimicrobial Chemotherapy, revealed how a PPMO
(peptide-conjugated phosphorodiamidate morpholino oligomer)
molecule could inhibit the enzyme, New Delhi
metallo-beta-lactamase, or NDM-1, that makes bacteria resistant
to a wide range of penicillins.
Lead researcher Bruce Geller from Oregon
State University said their research differs from previous
studies that worked on only one particular strain of bacteria.
"We’re targeting a resistance mechanism
that’s shared by a whole bunch of pathogens," said
Geller.
"It’s the same gene in different types
of bacteria, so you only have to have one PPMO that’s
effective for all of them, which is different than other PPMOs
that are genus specific."
This new molecule was tested successfully
in mice and is expected to be ready for human trials in three
years.
“We’ve lost the ability to use many of
our mainstream antibiotics,” Geller said.
“Everything’s resistant to them now.
That’s left us to try to develop new drugs to stay one step
ahead of the bacteria, but the more we look the more we don’t
find anything new. So that’s left us with making modifications
to existing antibiotics, but as soon as you make a chemical
change, the bugs mutate and now they’re resistant to the new,
chemically modified antibiotic.”
The scientists believe however that this
PPMO could be the answer to the crisis facing the healthcare
sector.
“A PPMO can restore susceptibility to
antibiotics that have already been approved, so we can get a
PPMO approved and then go back and use these antibiotics that
had become useless,” Geller concluded.
The World Bank released a report at the end
of last year warning that human antibiotic resistance combined
with the rise of superbugs could potentially kill 10 million
people by 2050 and devastate some countries’ economies.
WARNING FROM RAEL: For those who don't use their
intelligence at its full capacity, the label "selected by RAEL"
on some articles does not mean that I agree with their content
or support it. "Selected by RAEL" means that I believe it is
important for the people of this planet to know about what
people think or do, even when what they think or do is
completely stupid and against our philosophy. When I selected
articles in the past about stupid Christian fundamentalists in
America praying for rain, I am sure no Rael-Science reader was
stupid enough to believe that I was supporting praying to change
the weather. So, when I select articles which are in favor of
drugs, anti-semitic, anti-Jewish, racist, revisionist, or
inciting hatred against any group or religion, or any other
stupid article, it does not mean that I support them. It just
means that it is important for all human beings to know about
them. Common sense, which is usually very good among our
readers, is good enough to understand that. When, like in the
recent articles on drug decriminalization, it is necessary to
make it clearer, I add a comment, which in this case was very
clear: I support decriminalizing all drugs, as it is stupid to
throw depressed and sad people (as only depressed and sad people
use drugs) in prison and ruin their life with a criminal record.
That does not mean that there is any change to the Message which
says clearly that we must not use any drug except for medical
purposes. The same applies to the freedom of expression which
must be absolute. That does not mean again of course that I
agree with anti-Jews, antisemites, racists of any kind or
anti-Raelians. But by knowing your enemies or the enemies of
your values, you are better equipped to fight them. With love
and respect of course, and with the wonderful sentence of the
French philosopher Voltaire in mind: "I disapprove of what you
say, but I will defend to the death your right to say it".
L'absence de virus dans ce courrier électronique a été vérifiée par le logiciel antivirus Avast.
www.avast.com