BRCT Missense mutations of BRCA1 gene in Breast Cancer patients from Zambia

[Lisa Shakachite]

Hello,

My name is Lisa Shakachite and I am a Master's student in Molecular Biology at the University of Zambia. I am currently in the process of determining the appropriate sample size for the study I have mentioned above. And I would like to find out if there is a specific statistical equation that can help me determine this in order for me to either accept or reject my formulated null hypothesis?

Any assistance you can provide me with is greatly appreciated.

Kind regards,

Lisa Shakachite.

[Thomas Ngambwa]

what is the title of your study? unless we get this, you cannot be guided accordingly.

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[dakup fwenshinen]

There's a formula but it largely depends on your topic age range etc

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[Lisa Shakachite]

Hello all,

The title of my study is ‘BRCT Missense mutations of BRCA1 gene in Breast Cancer patients from Zambia’ and the goal of my study is to determine whether changes in the sequence of the BRCA1 protein affect its structure and function in Breast cancer patients. The selected sample size will specifically include females diagnosed with breast cancer aged 40 years old or younger. Samples will be collected randomly from a selected breast cancer referral clinic in Zambia meaning samples will cover a wide number of townships in the area. I hope this information is helpful. Any assistance you can provide is greatly appreciated.

Thank you,

Lisa.