TopPIC

Hi, Mozhan, You need to sum up the intensities of isotopic peaks (XIC) in all MS1 scans and multiple

Dear developers, When I was running several samples on TopFD v1.6.2, there was always an error as

Hi, Wingkin, Please check if you have enough hard drive space for storing indexes. Xiaowen From: top-

Hi, I am trying to run TopIndex with my fasta database and the following error was resulted:

Hi, Ziwei, TopPIC searches for truncated proteoforms with its default setting. We do not have a

Hi, Shujia, We have fixed the bug in TopPIC version 1.6.4, which has been released yesterday. You can

Hi, Qianjie, You can compute errors in precursor masses by comparing the values in the columns "

Hi, Jim, We have fixed the problem in TopFD. You can download the latest version TopPIC 1.5.4 from

James, Thank you for answering the question. Xiaowen On Thursday, March 24, 2022 at 2:22:13 PM UTC-5

Hi, James, Thank you for letting us know. We will look into it and keep you updated. Xiaowen On

Can you check if the folder C:\toppic_suite\topic\ contains the file libboost_filesystem-mt.dll? If

Hi, Michal, Thank you for using TopPIC. I think the problem is that TopPIC does not accept file names

Hi Xiaowen, now I could download it for Windows, thank you for the fast answer. I will try the new

Hi, Mowei, - I don't know if v1.5 topFD had some changes and I will need to rerun topFD with v1.5

Hi, Mowei, Thank you for the question and your report of the error. We will test the problems and

Hi, Konrad, The current version of TopPIC does not support EThcD. You can use either ETD or HCD for

Hi Xiaowen, Thanks - that makes sense. - James On Tuesday, October 19, 2021 at 6:55:36 AM UTC-7

Hi, Preston, Setting the precursor window to 0.8 m/z was correct. You do not need to try 0.4. We will

Hi, Konrad, The current version of TopPIC supports N-terminal modifications of whole proteoforms or

We investigated into this issue, and it turned out that the gene was somehow incorrectly annotated in

Hi, Qianjie, Another user reported a similar problem about crashing at the step of outputting tables,

Hi, Somak, The reason that you did not get a hit might be that the proteoform spectrum match is

Hi, Sean, Ms1.msalign files reported by topfd are located in a file folder. If your data file is

1. The UVPD label was not registered in MSConvert/TopFD, causing subsequent errors in TopMG. The UVPD

I see. Thank you so much. liuxia...@gmail.com在 2020年8月11日星期二下午10:47:21 [UTC+8]寫道： Hi, Kin Wing, >

We have fixed the bug in TopPIC 1.3.4. You can download the new version at http://proteomics.

Great. If your data set does not provide the information of precursor masses, you may need to set the

Hi, Francis, Thank you for using TopPIC and your feedback is important for us to improve TopPIC. We

Hi, Samantha, We need to consider several cases. (1) When the identified proteoform does not have any

Kasper, Thank you for sharing the information with us. We will fix the problem in the next release of