TopPIC

Hi, Preston, Thank you for using TopFD. There is an argument in TopFD that can set the maximum charge

Wenhao, You need to click “Add” in MSconvert to make sure that the centroiding function is applied.

Hi, John, You can download TopPIC 1.6.5 from https://www.toppic.org/software/toppic_backup/toppic_1.6

Hi, Preston, If you can share with us an MS3 data, ,we will check if we can add a function to TopFD

Hi, Ayesha, How the -K option is expected to function? Should decoy matches explicitly appear in the

Hi Dr. Liu, I have started running a combined file with the latest version 1.7.8 and faced issues

Hi, Mehrdad, The function has not been added to the GUI of TopPIC. Xiaowen From: top-down-toppic@

Hi Dr. Liu, I am a Ph.D. student in Dr. Liang Liang Sun's group at Michigan State University and

Dear Developers, I have been trying to run the TopPic for my samples but I keep getting the error

Hi, Mozhan, You need to sum up the intensities of isotopic peaks (XIC) in all MS1 scans and multiple

Dear developers, When I was running several samples on TopFD v1.6.2, there was always an error as

Hi, Wingkin, Please check if you have enough hard drive space for storing indexes. Xiaowen From: top-

Hi, I am trying to run TopIndex with my fasta database and the following error was resulted:

Hi, Ziwei, TopPIC searches for truncated proteoforms with its default setting. We do not have a

Hi, Shujia, We have fixed the bug in TopPIC version 1.6.4, which has been released yesterday. You can

Hi, Qianjie, You can compute errors in precursor masses by comparing the values in the columns "

Hi, Jim, We have fixed the problem in TopFD. You can download the latest version TopPIC 1.5.4 from

James, Thank you for answering the question. Xiaowen On Thursday, March 24, 2022 at 2:22:13 PM UTC-5

Hi, James, Thank you for letting us know. We will look into it and keep you updated. Xiaowen On

Can you check if the folder C:\toppic_suite\topic\ contains the file libboost_filesystem-mt.dll? If

Hi, Michal, Thank you for using TopPIC. I think the problem is that TopPIC does not accept file names

Hi Xiaowen, now I could download it for Windows, thank you for the fast answer. I will try the new

Hi, Mowei, - I don't know if v1.5 topFD had some changes and I will need to rerun topFD with v1.5

Hi, Mowei, Thank you for the question and your report of the error. We will test the problems and

Hi, Konrad, The current version of TopPIC does not support EThcD. You can use either ETD or HCD for

Hi Xiaowen, Thanks - that makes sense. - James On Tuesday, October 19, 2021 at 6:55:36 AM UTC-7

Hi, Preston, Setting the precursor window to 0.8 m/z was correct. You do not need to try 0.4. We will

Hi, Konrad, The current version of TopPIC supports N-terminal modifications of whole proteoforms or

We investigated into this issue, and it turned out that the gene was somehow incorrectly annotated in

Hi, Qianjie, Another user reported a similar problem about crashing at the step of outputting tables,