Next to disabling filters, you have 2 options. First, you could do this in your global configuration:
IISpeed Disallow /CKEditor/*
Disallow supports wildcard matching.
Alternatively, you can add a path like you already did:
path:/CKEditor/.*
IISpeed off
! # make sure noone enables it again later on.
IISpeed off makes IISpeed bail out very early in request processing in IIS.
You should be able match multiple paths like this, so you don't have to duplicate configuration.
path:/(CKEditor|CKFinder)/.*
One more thing:
There is a blacklist of (mostly js) files that we shouldn't attempt to rewrite, and the js files from CKEdit are among them.
The current version of IISpeed has a bug which prohibits this blacklisting from working correctly,
but our development tree already has the fix in.
Let me know if this helped!
Otto