Here is an example from my setup:
python /scratch/fatemehs-fatemehs/calibration/PyWrfHydroCalib-master/calibOrchestrator.py 5 \
--optDbPath /scratch/fatemehs-fatemehs/calibration/IWAA_calibration5/DATABASE.db
In this example, I use the full path to calibOrchestrator.py and the full path to the SQLite database file. The important point is that --optDbPath should point to the actual DATABASE.db file, not just the database directory. The number 5 refers to the JOB ID used in my setup, so it may need to be changed depending on your database configuration.