Hi Dani,
As far as I know, If you change the parameters in TBL file and then run the script to convert 2d files, then it is as good as you run without 2d files. You are supposed to change the 2d file to reflect spatial variability in parameters. This option is useful if you are running this model for multiple basins or a large basin having many sub-basins.
Everyone, Please correct me if I am wrong.
Thank you