Problem with bigBed for methyl array 450K for hg38 ?

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F. Vdm

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Feb 20, 2026, 10:30:27 AMFeb 20
to UCSC Genome Browser Public Support
Hi there,


Thanks for maintaining UCSC and helping us !

I recently downloaded 450K bigBed for hg38 build from there : https://hgdownload.soe.ucsc.edu/gbdb/hg38/bbi/illumina/

And after conversion to BED I noticed it contains only ~ 129K probes
=> Which is quite few compared to same file on hg19 build (and compared to its name = "450K")

Am I the only one seeing this ? Could it be an issue with this bigBed ?


Thanks for your help !
Best,
Felix.

Maximilian Haeussler

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Feb 25, 2026, 11:23:15 AMFeb 25
to F. Vdm, UCSC Genome Browser Public Support
Hi Felix,

The person who made this track, Brooke Rhead, told us that the track highlights the target regions of the probes, not the probes themselves. 

We were unable to find the exact probes when we looked into it so we loaded as a track what we got from Brooke. 

If you need the probes, you'll probably need to reach out to your Illumina support rep and CC us. Since we're not customers of Illumina directly, we were unable to get very far back when we added this track.

We will document this caveat in the track documentation page.

best
Max
 

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