Hello, Deepak.
Thank you for your interest in the Genome Browser and for sending your inquiry.
Could you share the bigWig URLs that result in this error to do more testing? If you don't want to share this information with our publicly-archived mailing list (gen...@soe.ucsc.edu), you can send it to our confidential support list at genom...@soe.ucsc.edu.
Does clicking the "refresh" button in the Genome Browser help?
Please include gen...@soe.ucsc.edu in any replies to ensure visibility by the team. All messages sent to that address are archived on a publicly-accessible Google Groups forum. If your question includes sensitive data, you may send it instead to genom...@soe.ucsc.edu.
Gerardo Perez
UCSC Genomics Institute
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