what is a canonical transcript?
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Sergei Manakov
Oct 9, 2012, 12:37:16 AM10/9/12
to gen...@soe.ucsc.edu
Hello,
I would like to know the definition of a canonical transcript, but I
am having trouble to find a definition. I would appreciate if somebody
could let me know or point at a page where it is explained.
thanks,
Sergei
--
Sergei (Siarhei Manakou) Manakov
California Institute of Technology
MC 147-75
land: +1 626 395 3593
mobile: + 1 858 729 4531
I would like to know the definition of a canonical transcript, but I
am having trouble to find a definition. I would appreciate if somebody
could let me know or point at a page where it is explained.
thanks,
Sergei
--
Sergei (Siarhei Manakou) Manakov
California Institute of Technology
MC 147-75
land: +1 626 395 3593
mobile: + 1 858 729 4531
Greg Roe
Oct 10, 2012, 3:27:19 PM10/10/12
to Sergei Manakov, gen...@soe.ucsc.edu
Hi, Sergei.
There's not a straightforward answer to this question, as different definitions exist. For example, Ensembl and and UCSC have different conventions for choosing the canonical transcript at each locus, but we each make an effort to choose the most likely one to give a real protein of the longest possible open reading frame.
Read the UCSC Genes description page (esp. Methods) for our "definition":
http://genome.ucsc.edu/cgi-bin/hgTrackUi?g=knownGene&db=hg19
- Greg
There's not a straightforward answer to this question, as different definitions exist. For example, Ensembl and and UCSC have different conventions for choosing the canonical transcript at each locus, but we each make an effort to choose the most likely one to give a real protein of the longest possible open reading frame.
Read the UCSC Genes description page (esp. Methods) for our "definition":
http://genome.ucsc.edu/cgi-bin/hgTrackUi?g=knownGene&db=hg19
- Greg
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