Hello,
Thank you for contacting the UCSC user support team.
We recommend contacting the IGV help desk, https://software.broadinstitute.org/software/igv/?q=contact, to help resolve your issues. Following your steps, we were able to reproduce the error you shared when using the desktop application. However, using the IGV webapp had no issues loading the bigBed file, so we are not sure what the issue is, but one of our engineers suspects that the chromosome names may be different between the bigBed file and the names used for the T2T assembly on IGV.
I hope this is helpful. If you have any further questions, please reply to gen...@soe.ucsc.edu.
All messages sent to that address are archived on a publicly accessible Google Groups forum.
If your question includes sensitive data, you may send it instead to genom...@soe.ucsc.edu.
Jairo Navarro
UCSC Genome Browser
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