hg38 with decoy sequences

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Albert Vilella

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Sep 9, 2014, 1:14:28 PM9/9/14
to gen...@soe.ucsc.edu
Hi,

Is there a hg38 genome reference with decoy sequences? How was it produced?

Thanks,

Albert.

Jonathan Casper

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Sep 10, 2014, 1:30:40 PM9/10/14
to Albert Vilella, gen...@soe.ucsc.edu

Hello Albert,

Thank you for your question about the hg38 human genome assembly. Many details about this assembly are available on our gateway page at http://genome.ucsc.edu/cgi-bin/hgGateway when you select the human/hg38 assembly. In particular, this assembly does include two versions of an analysis set that contains Epstein-Barr virus sequence as a decoy. More information is available in NCBI's README file for the analysis set at ftp://ftp.ncbi.nih.gov/genbank/genomes/Eukaryotes/vertebrates_mammals/Homo_sapiens/GRCh38/seqs_for_alignment_pipelines/README_ANALYSIS_SETS and in the parent README for the hg38 assembly at ftp://ftp.ncbi.nih.gov/genbank/genomes/Eukaryotes/vertebrates_mammals/Homo_sapiens/GRCh38/README.

You may also be interested in NCBI's Insights site, which gives more information about NCBI resources and the work underlying them. You can find the posts tagged "GRCh38" at http://ncbiinsights.ncbi.nlm.nih.gov/tag/grch38/.

I hope this is helpful. If you have any further questions, please reply to gen...@soe.ucsc.edu or genome...@soe.ucsc.edu. Questions sent to those addresses will be archived in publicly-accessible forums for the benefit of other users. If your question contains sensitive data, you may send it instead to genom...@soe.ucsc.edu.

--
Jonathan Casper
UCSC Genome Bioinformatics Group



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