CRISPR display

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Michael Lewis Goldberg

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Dec 9, 2020, 1:21:00 PM12/9/20
to gen...@soe.ucsc.edu, Kristina Anne Blake-Hodek
Hello,
We have been using your browser in a teaching lab with great success for several years.
Recently, there has been a change in the browser’s behavior that is potentially a headache for us.
Most of our work is with the Drosophila melanogaster database.
In the past, when we display the CRISPR targets, we could click on individual targets (that is, the green, yellow, and red bars) and would be directed to a screen that had an extremely useful table summarizing the features of the target including the guide and PAM sequences and the off-target sites.
Now, when clicking on individual target sites, we are directed to a page that is (at least for us) much less useful, with little information about the target but a lot of general description information about Display Conventions.
I’m putting some screen shots of the old and new outputs below.

We realize that there is a less convenient option that works at least some of the time, which is to use the link at the top of the page to Crispor.org.
Is this a temporary situation, or have you decided to ditch the CRISPR feature table for good and offload the duties to Crispor.org? Or perhaps there is a setting that we need to reset in order to visualize the feature table again?

Thanks for your response and for creating such a useful genome browser!

Best,
Mike Goldberg
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Michael L. Goldberg
Dept. of Molecular Biology & Genetics
425 Biotechnology Building
Cornell University
Ithaca, NY 14853-2703
Telephone: 607-254-4802
FAX: 607-255-6249
e-mail: ml...@cornell.edu




Jairo Navarro Gonzalez

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Dec 10, 2020, 6:00:25 PM12/10/20
to Michael Lewis Goldberg, gen...@soe.ucsc.edu, Kristina Anne Blake-Hodek

Hello,

Thank you for using the UCSC Genome Browser and reporting your issues.

We have fixed the issue where the extra CRISPR information was not showing up on the details page. The bug fix is going to be released to the public site in the next software update, which is scheduled to be released on Dec. 15th.

For now, you can use our development site (https://genome-preview.soe.ucsc.edu/) to use the CRISPR track with the missing information on the details page:

https://genome-preview.soe.ucsc.edu/cgi-bin/hgc?db=dm6&c=chr2L&l=835448&r=835899&o=835603&t=835626&g=crisprTargets&i=

I hope this is helpful. If you have any further questions, please reply to gen...@soe.ucsc.edu.
All messages sent to that address are archived on a publicly-accessible Google Groups forum.
If your question includes sensitive data, you may send it instead to genom...@soe.ucsc.edu.

Jairo Navarro
UCSC Genome Browser

Want to share the Browser with colleagues?
Host a workshop: https://bit.ly/ucscTraining


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