Technical Issues: Failed to open bigWig files for UCSC Browser + CistromeDB loading failure

[奶黄包]

Hi,

Thanks a lot for developing this valuable database.

Recently, I have been encountering issues when loading tracks on the UCSC Genome Browser redirected from your platform.

I use the Cistrome Data Browser (URL: https://cistrome.org/db/#/) to search for transcription factors such as YY1, CREB1, FOXK1 and so on to identify their target binding genes. After selecting datasets of interest under the Results tab, I attempt to visualize track signals for my candidate target genes via the UCSC Genome Browser. Unfortunately, an error continually appears on the UCSC page: Warning/Error(s): Couldn't open http://dc2.cistrome.org/genome_browser/bw/56052_treat.bw.

Furthermore, a 'loading failure' alert frequently displays in the top-right corner right after I open the CistromeDB webpage. I have attempted access at different times and on multiple computers, yet the issue remains unresolved. I am located in China with a domestic IP address, and I have tested both Microsoft Edge and Google Chrome browsers.

Additionally, relevant screenshots are attached for your reference.

I would highly appreciate your guidance and solutions to fix these connection problems!

Best regards,

Miao Yu

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奶黄包 9233...@qq.com

 

[Mengya Chen]

Dear Dr. X. Shirley Liu and Liu Lab members,

Thank you sincerely for developing and maintaining the CistromeDB database, which is an essential tool for my chromatin immunoprecipitation analysis work.