Hello Everyone,
We are pleased to announce the Genome Aggregation Database (gnomAD) Constraint Metrics track, previously only on hg19, is now also available on the human GRCh38/hg38 genome assembly.
These data show various metrics of pathogenicity per-gene as predicted for gnomAD v2.1.1 and identifies genes subject to strong selection against various classes of mutation. It is comprised of four subtracks:
More information on this track can be found in the track description page, as well as the gnomAD site. We would like to thank the Genome Aggregation Database Consortium for making these data available. We would also like to thank Lou Nassar, Maximilian Haeussler, Anna Benet-Pages, and Gerardo Perez for their work in creating and releasing these tracks.