New GENCODE "KnownGene" V44 for human (hg38) and VM33 for mouse (mm39)

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Gerardo Perez

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Sep 8, 2023, 4:47:34 PM9/8/23
to genome-...@soe.ucsc.edu

Hello Everyone,

We are pleased to announce the release of the GENCODE V44 (hg38) and the GENCODE VM33 (mm39) gene tracks. The GENCODE "KnownGene" V44 for hg38 and VM33 gene tracks were built using a UCSC pipeline (KnownGene) and the GENCODE comprehensive gene set to generate high-quality manual annotations merged with evidence-based automated annotations. The GENCODE "KnownGene" tracks are our default gene tracks, which have extensive associations to external sources. This allows for additional metadata on every item as well as external links. The track description pages contain options for configuring the display, such as showing non-coding genes, splice variants, and pseudogenes. The track description pages for these tracks contain options for configuring the display such as also showing non-coding genes, splice variants, and pseudogenes.

Below is a summary of the contents found in each release. For more details visit the GENCODE site.

GENCODE v44 Release Stats
GenesObservedTranscriptsObserved
Protein-coding genes19,396Protein-coding transcripts89,067
Long non-coding RNA genes19,922- full length protein-coding63,968
Small non-coding RNA genes7,566- partial length protein-coding25,099
Pseudogenes14,735Nonsense mediated decay transcripts21,384
Immunoglobulin/T-cell receptor gene segments647Long non-coding RNA loci transcripts58,246
Total No of distinct translations65,342Genes that have more than one distinct translations13,594

GENCODE VM33 Release Stats
GenesObservedTranscriptsObserved
Protein-coding genes21,403Protein-coding transcripts58,750
Long non-coding RNA genes14,842- full length protein-coding45,112
Small non-coding RNA genes6,105- partial length protein-coding13,638
Pseudogenes13,809Nonsense mediated decay transcripts7,218
Immunoglobulin/T-cell receptor gene segments701Long non-coding RNA loci transcripts26,564
Total No of distinct translations44,993Genes that have more than one distinct translations10,893

We would like to thank the GENCODE project for providing these annotations. 

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