New DNA Methylation track: Human Methylation Atlas Summary and Signals tracks

[Gerardo Perez]

Hello Everyone,

We are excited to announce the release of the Human Methylation Atlas Summary and Signals tracks for hg38 and hg19, available in the DNA Methylation superTrack. The Human Methylation Atlas tracks display genome-wide DNA methylation profiles from deep whole-genome bisulfite sequencing (WGBS) of 39 primary human cell types sorted from 205 healthy tissue samples.

The Human Methylation Atlas Summary track consists of three subtracks:

• All Unmethylated Regions - unmethylated genomic regions for each of the 39 cell types.
• Putative Enhancers from Unmethylated Regions - putative enhancers derived from unmethylated regions for 32 of the 39 cell types.
• Top 250 Unmethylated Regions per Cell Type - the top 250 most specifically unmethylated regions in each of the 39 cell types.

The Human Methylation Atlas Signals track displays per-cell-type methylation beta values (0-1 scale) across the genome, with merged tracks combining all replicates per cell type and replicate tracks for each individual sample.

We would like to thank the Dor, Kaplan, and Glaser laboratories at the Hebrew University of Jerusalem and collaborating institutions for generating and providing these data.