[genome-announce] New dbSNP build 151 tracks now available for hg19 and hg38
Jairo Navarro Gonzalez
We are pleased to announce the release of our "SNP" tracks derived from NCBI's dbSNP Human Build 151 data, available on the two most recent human assemblies, GRCh38/hg38 and GRCh37/hg19. This release will again double in size to about 650 million variants compared to the previous 150 release (300 million for hg38, and over 200 million for hg19).
There are four SNP tracks available as part of this release:
- All SNPs (151): containing all mappings of reference SNPs to the human assembly. The tracks below are subsets of All SNPs (151).
- Common SNPs (151): uniquely mapped variants that appear in at least 1% of the global population or are 100% non-reference.
- Flagged SNPs (151): uniquely mapped variants, excluding Common SNPs, that have been flagged by dbSNP as "clinically associated."
- Mult. SNPs (151): variants that have been mapped to more than one genomic location. This track has been shrinking over the course of the last few releases as dbSNP now excludes most SNPs whose flanking sequences map to multiple locations in the genome.
The graph above shows the increasing growth of variants in the All SNPs track, by dbSNP release number, and the stagnant growth of the Common SNPs track, essentially stuck at 14.8 million variants.
By default, only the Common SNPs (151) are visible in the browser; other tracks must be made visible using the track controls. All four SNP tracks reside in the "Variation" group category for the hg19 and hg38 genome browsers.
We want to thank Angie Hinrichs, Robert Kuhn, and Jairo Navarro for their work on creating and analyzing the data. We'd also like to thank the dbSNP group at NCBI for providing access to the data.