Requesting Permission for Significant Web Requests

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Matthew Snyder

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Mar 26, 2015, 12:59:13 PM3/26/15
to gen...@soe.ucsc.edu
Good Morning,

My company would like to use your In-Silico PCR site to generate GRCh37 coordinates for roughly 3,000 of our primers. We have written code to use your site to generate the coordinates and amplicon information for many of our primers per second. As such, we would be processing a lot of web requests in a short amount of time. 

I am contacting you to make sure this is alright, as we do not want to have our IP banned from using your important tools. If this is okay, will our processes be throttled down? We can also change the rate of requests to whatever you would like to ensure we can still use the site to generate the GRCh37 coordinates and amplicon sequences for all of our primers. 

Thank you for your time. I look forward to hearing from you.

Best regards,
Matthew 

Matthew Snyder

Medical Neurogenetics, LLC.

msn...@mnglab.com

www.mnglab.com

 
 

Matthew Speir

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Mar 31, 2015, 5:30:59 PM3/31/15
to Matthew Snyder, gen...@soe.ucsc.edu
Hi Matthew,

Thank you for your questions about the programmatic access of our In-Silico PCR tool. The "Conditions of Use", https://genome.ucsc.edu/#Conditions, section on the UCSC Genome Browser home page contains information about program-driven access of the tools on our site:

    "Program-driven use of this software is limited to a maximum of one hit every 15 seconds and no more than 5,000 hits per day."

You may also want to consider the command line version of isPCR, which is available for commercial use with the purchase of a license. You can contact Kent Informatics, http://www.kentinformatics.com/index.html, for more information about purchasing a commercial license for isPCR.

I hope this is helpful. If you have any further questions, please reply to gen...@soe.ucsc.edu. All messages sent to that address are archived on a publicly-accessible Google Groups forum. If your question includes sensitive data, you may send it instead to genom...@soe.ucsc.edu.

Matthew Speir
UCSC Genome Bioinformatics Group
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