New GTEx Allele Specific Expression Hub Available

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Christopher Lee

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Aug 30, 2016, 5:46:57 PM8/30/16

to genome-...@soe.ucsc.edu, Kate Rosenbloom

We are pleased to announce the release of Allele Specific Expression (ASE) data for the human hg19 and hg38 assemblies. ASE data from the Lappalainen Lab at the New York Genome Center is now available in the UCSC Genome Browser as a public track hub. This track hub contains ASE data identified from transcriptome and genotype data in 53 tissues collected by the Genotype-Tissue Expression (GTEx) project and analyzed by the Lappalainen Lab. The hub contains 3 tracks, a cross tissue summary via density graph of median allelic imbalance, a summary track of all SNPs with evidence of ASE in any tissue, and a composite track showing ASE on a tissue by tissue basis. In the composite track each subtrack is colored based on median ASE for the site across all samples of the tissue, shaded on a spectrum of gray (low) to GTEx convention tissue color (high).

To access and view this hub, navigate to the Track Hub gateway page and select "GTEx Analysis Hub" from the Public Hubs list. Please direct any queries to Stephane Castel.

Many thanks to Stephane Castel and the Lappalainen Lab at the NY Genome Center for providing this data!