phyloP46way bigwig files

[Öztürk, Hakime]

Hello,

I'd like to get PhyloP46way scores with VEP custom function. In the definition of --custom flag it says that files must be tabix indexed or in the bigWig format.

    phyloP100way conveniently has bw files under this directory.
    ftp://hgdownload.soe.ucsc.edu/goldenPath/hg19/phyloP100way/

    But for phyloP46way, there is no bw file, but multiple folders.
    ftp://hgdownload.soe.ucsc.edu/goldenPath/hg19/phyloP46way/
  

Is it possible to have bigWig files for phyloP46way​ too?

Thanks a lot!

Hakime 

[Matthew Speir]

Hello, Hakime.

Thank you for your question about bigWig files for the 46-way phyloP scores.

These bigWig files are now available on our downloads server: http://hgdownload.soe.ucsc.edu/goldenPath/hg19/phyloP46way/. There is one for each of the subsets (placental and primates) and one that includes all of the species in the alignment.

While you didn't specifically request them, the phastCons bigWig files are also available: http://hgdownload.soe.ucsc.edu/goldenPath/hg19/phastCons46way/.

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Matthew Speir

UCSC Cell Browser, Quality Assurance and Data Wrangler

Human Cell Atlas, User Experience Researcher

UCSC Genome Browser, User Support

UC Santa Cruz Genomics Institute

Revealing life’s code.

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