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The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level
by Jessica Wapner
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Descriptions :
Synopsis : One of Publishers Weekly?s Top Ten Spring 2013 Science BooksPhiladelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research?the Philadelphia chromosome. This book charts not only that landmark discovery, but also?for the first time, all in one place?the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings
Details :
Author : Jessica Wapner
Pages : 320 pages
Publisher : The Experiment
Language : en-US
ISBN-10 : 1615190678
ISBN-13 : 9781615190676