Just a note to encourage people to try reading Tagged PDF in Firefox.
Versions above 148 (currently beta) will pass the Tagged PDF structure tree including MathML to NVDA, so Firefox joins Acrobat and Foxit as viable readers for Tagged PDF.
This should reach the stable default Firefox distibution at the end of February.
A video recording of NVDA reading a LaTeX generated PDF in firefox is at
along with some notes on what works and does not work in this initial implementation.
David
(I have no involvement with Firefox other than sending a few bug reports testing this recently, all of which got fixed)