The Java client driver 2.1 (branch 2.1) is compatible with Apache Cassandra 1.2, 2.0 and 2.1.
UDT and tuple support is available only when using Apache Cassandra 2.1 (see CQL improvements in Cassandra 2.1).
Other features are available only when using Apache Cassandra 2.0 or higher (e.g. result set paging, BatchStatement, lightweight transactions -- see What's new in Cassandra 2.0). Trying to use these with a cluster running Cassandra 1.2 will result in an UnsupportedFeatureException being thrown--
Olivier Michallat
Driver & tools engineer, DataStax
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