Simulated fMRI data on surface

[Reza Rajimehr]

Hi,

We want to generate simulated/random fMRI data for vertices of fs_lr surface, in a way to be as similar as possible to the HCP 7T fMRI data. These data should have two important features that are typically seen in BOLD fMRI: spatial autocorrelation and temporal autocorrelation. For the spatial autocorrelation, we can start with Gaussian white noise data, then smooth them on the surface using wb_command. However, we are not sure what is the right procedure for implementing the temporal autocorrelation. Do you have any recommendations or a script/function to share with us? There are some tools for this purpose (e.g. SimTB), but they don’t seem to be optimized for generating simulated data on surface.

Thanks,

Reza

[Glasser, Matt]

Couldn’t you do something similar with temporal smoothing?  fslmaths or matlab could do temporal smoothing.

Matt.

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[Reza Rajimehr]

Thank you Matt. Just wanted to make sure that the temporal smoothing is a right thing to do. With respect to the smoothing window, would 10 sec be appropriate, as the HRF typically takes about 10 seconds?

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[Glasser, Matt]

Well you could convolve a random timeseries with an HRF in matlab also…

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[Reza Rajimehr]

Oh yes, that is a right thing to do, thanks!

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