Unrelated subjects

[Zack Guo]

Dear HCP Experts,

I'm working with the HCP dataset and have a question about the lists for unrelated subjects. I found two different lists:

1. The "100 Unrelated Subjects" list (https://db.humanconnectome.org)

2. The " S900 Unrelated Subjects" list (https://wiki.humanconnectome.org/docs/S900%20Unrelated%20Subjects%20CSV.html)

I noticed that the list 2 is not a complete superset of the list 1. For example, subject 100307 is included in the "100 Unrelated" list but is not in the S900 list.

Could you please interpret how the "unrelated" is determined for these lists?  And would it be methodologically sound to merge the subjects from both lists to create a larger sample for my analysis?

Thank you very much for your kind consideration and I am looking forward to hearing from you.
Best regards,
Zack

[Tim Coalson]

100307 might have been excluded because a different participant with a family relation to them was chosen instead in the S900 list.  As such, it would not be sound to blindly merge the lists, as the result could have some subjects from the same family.

Tim

--
You received this message because you are subscribed to the Google Groups "HCP-Users" group.
To unsubscribe from this group and stop receiving emails from it, send an email to hcp-users+...@humanconnectome.org.
To view this discussion visit https://groups.google.com/a/humanconnectome.org/d/msgid/hcp-users/a51b538f-f3be-4328-a5c6-cde672cbe6c4n%40humanconnectome.org.

[Elam, Jennifer]

I can confirm that what Tim says about a different participant with a family relation to 100307 was chosen for the S900 list. When we made the S900 list we additionally stipulated that all unrelated subjects included had a T1, a T2, complete rfMRI, and physiological data.

 

Jenn

 

________________________________________

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
el...@wustl.edu
www.humanconnectome.org

 

To view this discussion visit https://groups.google.com/a/humanconnectome.org/d/msgid/hcp-users/CANm3QU7qf6Vkw-Btw_8cc7Cmj3ettFn7b4PVQrKF9NeVtp33GQ%40mail.gmail.com.

 

---

The materials in this message are private and may contain Protected Healthcare Information or other information of a sensitive nature. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this email in error, please immediately notify the sender via telephone or return mail.

[Zack Guo]

Thank you both Tim and Jenn for the very helpful and clear explanations.

I just have two quick follow-up questions to ensure I understand correctly:

1. For subjects who are in the "Unrelated 100" list but not the S900 list (like 100307), does this mean they are not "unrelated" in the context of the full S900 list?

2. I would like to include as many subjects as possible in the analysis. Could you please provide some advice?

Thank you again for your invaluable guidance.

Best regards,
Zack

[Elam, Jennifer]

Hi Zack,

Many, but not all, subjects in the Unrelated 100 that aren't listed in the S900 unrelated list have a sibling included in the S900 unrelated list. Putting together an unrelated list is complicated, especially if you want all the subjects in your list to have a particular type of data (such as the physiological measurements added as a criterion for the S900 unrelateds list). In order for you to compile a list with the maximum number for your analysis, you will need to obtain Restricted access so that you can see the family IDs and include only one family member in your list and you will need to refer to the completeness variables in the unrestricted behavioral data to filter for the subjects that have the data you need. The restricted access application requires your PI to also obtain restricted access since they are responsible for your use of the data.

Best,

Jenn

 

________________________________________

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
el...@wustl.edu
www.humanconnectome.org