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We did some work to get multi-echo supported by the HCP Pipelines as I had high hopes that it would improve fCNR as has been previously reported (and that one can see with some simplistic MR physical modeling). Unfortunately, when I did the head-to-head test that is not what I found (multi-echo was not bad, just not quite as good as a directly comparable single echo scan). This could be because prior literature has not accurately reported the multi-echo protocols including all variables that affect SNR/resolution and that effects of using different kinds of ICA denoising are being conflated with multi-echo fMRI. Thus, at this point I would recommend sticking with an optimized single echo scan.
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Andreas Bartsch
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Jul 14, 2024, 7:08:34 PM (2 days ago) Jul 14
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hi,
yes - this is my impression, too.
cheers,
andreas