[GA4GH] Review Requested: GKS-Core 1.1.0 Release
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Beatrice Amos
Dec 12, 2025, 9:47:08 AM12/12/25
to GA4GH Variation Representation, GA4GH Variant Annotation, Sequence Annotation, Product - Categorical Variation Representation Specification (Cat-VRS), GA4GH GKS Steering
Dear colleagues,
We made a 1.1.0 GKS-Core release with the new ConceptSet that was originally in VA. We're proposing a very minor breaking change to the way we handle domain entities. Before, we used to independently define domain entity sets (e.g. ConditionSet and TherapyGroup).
We will have a 1-week review period (with more time available on request). Please leave your review on the discussion: https://github.com/ga4gh/gks-core/discussions/126.
We made a 1.1.0 GKS-Core release with the new ConceptSet that was originally in VA. We're proposing a very minor breaking change to the way we handle domain entities. Before, we used to independently define domain entity sets (e.g. ConditionSet and TherapyGroup).
In our proposal, we've changed this to use a common class ConceptSet with restrictions on conceptType depending on where it's used.
The breaking change is the rename of the properties therapies and conditions to concepts. We're hoping this change will reduce the maintenance burden to handle various domain entities (in terms of schema and implementer code).
The breaking change is the rename of the properties therapies and conditions to concepts. We're hoping this change will reduce the maintenance burden to handle various domain entities (in terms of schema and implementer code).
We will have a 1-week review period (with more time available on request). Please leave your review on the discussion: https://github.com/ga4gh/gks-core/discussions/126.
The changes can be found here: https://github.com/ga4gh/gks-core/compare/1.0.0...1.1.0
Best,
Beatrice
On behalf of Kori Kuzma, Larry Babb and the GKS team
Beatrice
On behalf of Kori Kuzma, Larry Babb and the GKS team
Beatrice Amos
Dec 17, 2025, 5:00:33 AM12/17/25
to GA4GH GKS Steering, Work Stream - Genomic Knowledge Standards (GKS), GA4GH Variation Representation, Product - Categorical Variation Representation Specification (Cat-VRS), GA4GH Variant Annotation, Sequence Annotation
Dear colleagues,
A quick reminder that feedback on the proposed GKS-Core 1.1.0 changes closes tomorrow. If you haven't yet, please add your comments to the discussion here: https://github.com/ga4gh/gks-core/discussions/126.
If you need additional time to review, please pop the team a note and the window may be extended.
Thank you,
Beatrice
On behalf of Kori Kuzma, Larry Babb, and the GKS team
A quick reminder that feedback on the proposed GKS-Core 1.1.0 changes closes tomorrow. If you haven't yet, please add your comments to the discussion here: https://github.com/ga4gh/gks-core/discussions/126.
If you need additional time to review, please pop the team a note and the window may be extended.
Thank you,
Beatrice
On behalf of Kori Kuzma, Larry Babb, and the GKS team
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