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They probably would if you crushed them up and mixed them with some water, though you can’t necessarily do the water-mixing part of it ahead of time, as it’s not always stable to remain effective for long. You could potentially get the capsules, dump them out into a pre-measured dose, and then mix it with some water and dose it that way if needed.
The dosage range for dogs goes higher than the 1 mg per pound mentioned in the blog entry (which was extremely useful, I’m hanging onto it for my own practice). You could go up to about 2 mg per pound without a problem, I do it all the time for dogs with mast cell tumors that like to release histamine when they get angry. If you were carrying the 12.5 mg/5 ml children’s formulation, then 1-2 mg per pound would be 10-20 mg per ten pounds of body weight, or 4-8 mls of the liquid.
There are also oral suspensions of benedryl available in higher concentration of 25 mg/5 ml (5 mg/ml as opposed to 2.5 mg/ml).
The published dose for horses via oral route is about half that of dogs, or about ½ - 1 mg per pound of bodyweight. Thus, a 1000-lb horse dose is 200 mls (about 4 dosing syringes) of the higher concentration 25 mg/5 ml benedryl. If you obtained and opened up some of the capsules, then you’d need about 40 of them. Probably closer to 50, assuming some will get dribbled out on the ground.
There are also 50 mg diphenhydramine capsules available from an online pharmacy. I don’t know if they carry 50-mg caps at Costco, etc. It doesn’t require a vet’s prescription. A 100-count bottle of 50 mg capsules will cost you about twelve bucks. So 25 of those capsules would be about right for a 1000-pound horse.
Susan Garlinghouse, DVM
From: ridecampre...@googlegroups.com [mailto:ridecampre...@googlegroups.com] On Behalf Of KSherman
Sent: Monday, June 24, 2013 12:13 AM
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