Benadryl For Snake Bite

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Don Huston

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Jun 24, 2013, 12:13:56 AM6/24/13
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8oz of Childrens Liquid = 236 ml
5 ml has 12.5 mg of HCL (active ingredient)
So...236 / 5 x 12.5 = 590 mg of HCL

1 adult Benadryl tablet has 25 mg of HCL
So....590 / 25 = 24 tablets

If I assume that this 8oz dose (or 24 tablets) is for a 150lb human
then what would be a ballpark dose for a 900lb horse?
6 times or 144 tablets?

The reason I ask is the tablets would be easy to carry while riding
so I might as well carry enough to do the horse some good if necessary.

Don Huston


At 08:50 AM 6/23/2013 Sunday, you wrote:
>"Carry at least -2- 4oz bottles of childrens LIQUID Benadryl with
>you when you ride. Should you get bitten DRINK BOTH BOTTLES
>Immediately, 60% of the damage done by snakebites is done by your
>bodies own Histamine response. No you won't overdose if you drink
>two bottles... (remember its a pediatric mixture) but because its
>liquid you will absorb it faster.... Stop the Histamine response and
>you will suffer a much less intense reaction and have much less
>damage... Also it buys you about an extra 45 minutes to get help."
>Laney

KSherman

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Jun 24, 2013, 3:13:13 AM6/24/13
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The liquid is recommended because it's absorbed faster. Would the tablets be absorbed fast enough to stop the histamine response?
Kathy

K. Lynd

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Jun 24, 2013, 7:47:54 AM6/24/13
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So is 8 ounces of children's bendadryl about 12 times the recommended adult dose?
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ride...@juno.com

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Jun 24, 2013, 8:54:24 AM6/24/13
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>>>>The reason I ask is the tablets would be easy to carry while riding
so I might as well carry enough to do the horse some good if necessary.


My daughter Josie had a bad allergic reaction to a yellow jacket sting a couple of years and had to go to the emergency room for IV medication. Now we carry the epi-pen on rides but it's still scary when you're a long way from the truck in bee season. Then last year she got stung at home and took 2 Benadryl immediately and had no more reaction than I would have. We have been carrying a lot of the benadryl capsules that are individually packaged in our packs but those do not hold up well at all. When I checked the ones in my pack they've gotten damp and look rough. I'm thinking we'll start carrying the liquid but I guess that's prohibitive for a horse dose. Tablets may hold up better than the caplets.

I thought it was weird that the nose was the best place for a dog to get bitten...but then they can pant. I always thought that was the worst for a horse.

Angie




At 08:50 AM 6/23/2013 Sunday, you wrote:
>"Carry at least -2- 4oz bottles of childrens LIQUID Benadryl with
>you when you ride. Should you get bitten DRINK BOTH BOTTLES
>Immediately, 60% of the damage done by snakebites is done by your
>bodies own Histamine response. No you won't overdose if you drink
>two bottles... (remember its a pediatric mixture) but because its
>liquid you will absorb it faster.... Stop the Histamine response and
>you will suffer a much less intense reaction and have much less
>damage... Also it buys you about an extra 45 minutes to get help."
>Laney

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Susan Garlinghouse, DVM

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Jun 24, 2013, 4:55:42 PM6/24/13
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They probably would if you crushed them up and mixed them with some water, though you can’t necessarily do the water-mixing part of it ahead of time, as it’s not always stable to remain effective for long.  You could potentially get the capsules, dump them out into a pre-measured dose, and then mix it with some water and dose it that way if needed.

 

The dosage range for dogs goes higher than the 1 mg per pound mentioned in the blog entry (which was extremely useful, I’m hanging onto it for my own practice).  You could go up to about 2 mg per pound without a problem, I do it all the time for dogs with mast cell tumors that like to release histamine when they get angry.  If you were carrying the 12.5 mg/5 ml children’s formulation, then 1-2 mg per pound would be 10-20 mg per ten pounds of body weight, or 4-8 mls of the liquid.

 

There are also oral suspensions of benedryl available in higher concentration of 25 mg/5 ml (5 mg/ml as opposed to 2.5 mg/ml).

 

The published dose for horses via oral route is about half that of dogs, or about ½ - 1 mg per pound of bodyweight.  Thus, a 1000-lb horse dose is 200 mls (about 4 dosing syringes) of the higher concentration 25 mg/5 ml benedryl.  If you obtained and opened up some of the capsules, then you’d need about 40 of them.  Probably closer to 50, assuming some will get dribbled out on the ground.

 

There are also 50 mg diphenhydramine capsules available from an online pharmacy.  I don’t know if they carry 50-mg caps at Costco, etc.  It doesn’t require a vet’s prescription.  A 100-count bottle of 50 mg capsules will cost you about twelve bucks.  So 25 of those capsules would be about right for a 1000-pound horse.

 

Susan Garlinghouse, DVM

 

From: ridecampre...@googlegroups.com [mailto:ridecampre...@googlegroups.com] On Behalf Of KSherman


Sent: Monday, June 24, 2013 12:13 AM

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Laney Humphrey

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Jun 24, 2013, 10:55:12 PM6/24/13
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You just answered something I'd been wondering about Susan.  My small animal vet suggested that I give 28 lb. Ruby (dog) a whole benadryl tab if she gets stung again by an ant.  To my mind, used to human dosages, that seemed like a huge dose but I guess dogs react differently to benadryl than humans do.  That much would have me zonked out on the floor in no time!

Question: if benadryl isn't stable long term in water, what is the liquid in the liquid form?
Laney
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