The only drawback of pacing that I recall from the initial tests was that pacing delays sending packets... and hence there is a chance that it will increase latency (of a delayed packet at the tail end of a paced group). The results I
presented at IETF 88 showed (as I recall) that the pacing had a significant impact on reducing packet loss. So you are trading a risk of sending later... vs sending sooner, but having the packet dropped. <oops>. The conjecture of course was that a "burst" or "rapid train" of packets had a much better chance of instigating a buffer-overrun (and a packet loss) upon entry into a router that was operating close to its bloated limits.
When combined with FEC (with single-lost-packet recovery), the benefits seemed (at the time I was doing experiments) to be quite significant. Again, the results should be on slides in the
IETF 88 presentation on QUIC. Take a look at the graphs on the last few pages.
I think I also saw some interesting (negative) results for pacing too slowly. As I recall, if you sent packets close(r) together, they might (at some networking layer) be coalesced, and conveyed together. As a result, you'd typically then get all (both?) of them, or none of them. In contrast, if you paced things out, then you might suffer independent packet loss of one or the other. IF you system (receiver) needed both packets, then you'd rather go with the all-or-nothing plan (pace them closer together!). The analogy would be that if you were ordering skis, poles, and boots for a ski trip (this Saturday) from Amazon, you'd *much* rather have all items shipped in one box, assuming each box has a fixed loss probability. With separate boxes, there is a much higher chance that one of the boxes won't make it (right away), and you really want "all or nothing by Saturday."
YMMV... and this is all from distant memories.
Jim