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Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. ³. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.

One key difference is that oxycodone is more potent than hydrocodone. This means that it takes less oxycodone to produce the same effects as hydrocodone. Oxycodone is also more likely to be abused than hydrocodone because it produces stronger effects. This also means that oxycodone has a higher risk of overdose.