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Tramadol is an effective painkilling agent that is widely used to cut moderate to moderately-severe pain in adults. Find out about how to use the drug, its effectiveness, and safety profiles from the post.
Pain is hard to stand, especially if it doesn’t go away within hours and even days. The intake of painkillers becomes the only option for people dealing with such an issue.
Tramadol is among the most popular preparations to cope with pain in the United States. According to the statistic, over 4.8 million Americans use it.
Are you one of those pain sufferers?
Do you need an effective and time-tested preparation that will help you feel better and come back to your normal life?
Tramadol can be the solution you need.
But before you go and buy Tramadol online, we’d like to give you an in-depth look into how this medication works; how it can be helpful, and how it can be dangerous.
Tramadol has been present on the European market since 1977 and was approved for use in the United States in the middle 1990s.
Within the years of its use, Tramadol has proven its effectiveness in dealing with pain. There is a range of studies and clinical research that prove that preparation is more effective for pain relief compared to a placebo.
This preparation is an opioid, which acts in two ways. First is the binding of the substance metabolite, dysmetramadol, to the µ-opioid receptors.
Second is weak inhibition of norepinephrine and serotonin reuptake. Both actions are aimed to produce an analgesic effect and relieve pain.
The primary indication for Tramadol intake is the management of moderate and moderately-severe pain. The drug can be effectively used in patients suffering from acute pain in the post-surgery period and chronic pain associated with osteoarthritis.
Due to its high addiction potential, Tramadol belongs to Schedule IV controlled substances.
For this reason, the only way to legally buy Tramadol online or offline is by doctor’s prescription.
You’ve probably heard a lot of stories about Tramadol causing side effects and addiction. However, such things cannot be referred to every patient getting treatment with this drug.
In fact, the safety of using Tramadol significantly depends on how you do it.
To be on the safe side and minimize every risk associated with the intake of opiates, you should carefully follow the guidelines given by your doctor and stick to some general recommendations on Tramadol intake.
Here are the basics that will help you go through the therapy with Tramadol with minimum-to-no negative consequences:
- Take the prescribed dosage of the medication only. Never titrate your dose without agreeing with your doctor.
- Start the therapy with the lower dosages to prevent acute side effects. It’s better to gradually increase the dose until you reach the desired therapeutic effect.
- If you have any major health issues, tell your doctor about them as there is a chance you may need a dose adjustment to avoid Tramadol overdose.
- Food doesn’t affect the absorption of the drug, so you may take it regardless of meals.
- Whenever you feel the effects of the drug become weaker or last less than they used to, contact your doctor for advice. There is a chance you are building up a tolerance to the drug and may need a dose adjustment or switching to some other non-opioid painkiller.
Due to a range of medical reasons, you may be not recommended to take Tramadol to soothe the pain. What are these? Let’s see this in the list below:
- Hypersensitivity to Tramadol or other components of the preparation or other opioids;
- Acute intoxication with some medical preparations or alcohol;
- Ongoing suicidal thoughts or suicidal attempts in the past;
- A history of substance abuse;
- Depression
Opioid analgesics are not recommended to children under the age of 16 due to a lack of evidence of its safety in this group of patients.
Despite the drug label claims pregnant individuals can use Tramadol when the expected benefits for the mother prevail over the possible risks for the fetus, the post-marketing experience of using Tramadol in gestation revealed a range of negative consequences for such patients.
Among the reported events, there are:
- Neonatal seizures;
- Stillbirth;
- Fetal death;
- Withdrawal syndrome in newborns.
Taking these into account, you should better avoid taking Tramadol and other opioids during pregnancy. Lactating individuals should stop breastfeeding their babies if they initiate treatment with this preparation.
While Tramadol is generally considered one of the safest representatives of opioid analgesics, this preparation still has a range of side effects that may appear in the course of treatment.
Below are the most commonly reported adverse events related to this drug:
- Dizziness;
- Headache;
- Nausea and vomiting;
- Constipation;
- Drowsiness;
- Sweating;
- Mouth dryness.
The incidence and severity of listed reactions progress with the extension of the term of treatment and the dose increase.
So the longer you take Tramadol, the more likely you become to develop unwanted reactions.
Steven Harris
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