Hi Rodney,
Just a testimony as I have no real solution either.
We are seeing the same kind of problem for a while (Chrome not starting the extension, extension code never executed).
For us, it happens only for MacOS users (with multiple Chrome profiles synced). Neither uninstalling / reinstalling the extension nor restarting Chrome helps.
The only solution we found to get it back is to remove the Chrome profile from the Chrome profile menu and re-create it.
We first thought it was due to a corrupted profile but it happens very often (mostly after an extension update / install as we always have MacOS users impacted during internal non-regression testing which starts by updating / installing the latest version of the extension)