Self built version of Chromium, gn args:
is_official_build = true
media_use_ffmpeg = true
media_use_libvpx = true
proprietary_codecs = true
ffmpeg_branding = "Chrome"
enable_widevine = true
symbol_level = 0
enable_nacl = false
Using
https://html5test.com/ i've found that Chromium doesn't support variable bitrate streaming (MPEG-DASH, HLS), which makes using Spotify and Twitch impossible.
Chromium also doesn't have support for TS (I think this is a container). I haven't found a case where this is an issue yet, but it could be a problem.