This problem has been growing worse in worse with each version of Chrome. It's to the point now where I'm about to ditch it entirely.
DNS Caching. I'll use my local windows host file to change IP addresses when migrating sites to new hosts. The change is instant in windows but Chrome caches DNS and does not bother rechecking... so I'm stuck until I restart chrome. And yes I do know how to clear the DNS cache but it doesn't seem to work... or at least not instantly. There is a lot of waiting/ restarting.
The same problem happens with CSS/HTML files. I'll make changes to CSS and chrome, even when I press F5 doesn't bother to get the latest file. It pulls from the cache meaning I have to delete it and reload, which is time-consuming. And yes I realize there are many components that could create HTTP cache headers.... but that is not the case here. Literally, Chrome is starting to suck BIG LEAGUE... I can open up Firefox or even Edge and I refresh and my changes are shown.
My last complaint is not being able to bypass HTST SSL issues. Like I get it, but again if I'm developing something or migrating... This issue holds me up and is a pain in my butt. There has to be a developer mode for chrome that ditches all the apples-esque tweaks that have been made that take control and functionality away and replace it for dumbed down mass consumer use.
Please make Chrome great again...