We currently ship the 64-bit-preferred version of Chrome/WebView to devices with at least 6.5GB of RAM available to the kernel. This effectively means devices that are marketed as having 8GB RAM (the actual amount available to the kernel is typically quite a bit lower than the physical amount of RAM on the board due to carveouts for GPU/modem/etc). The impact of the additional memory usage on these devices was minimal in our experiments.
This doesn't mean it won't work on devices with less RAM, but the increased systemwide memory pressure will mean that background apps get OOM killed more frequently, and are more likely to have to cold start if users switch back to them.