VsChromium is indeed very helpful for code search. It consumes several GB of RAM (it loads all of Chrome's source into RAM) so that it can do quick searches, but on a 64 GB machine this should not be a problem.
VS should be able to debug Chrome fairly efficiently. I just tested now and from when I pressed F11 (step in) to when the debugger was stopped in WinMain took about five seconds. This is with VS 2019. I then pressed F5 (run) and Chrome was running about five seconds later. If this was my first time debugging then it would take longer because symbols would need to be downloaded, but during this time there would be minimal CPU usage.
This was with a release build. A debug build would be a bit slower because there is more code generated and more debug information, but should still be manageable.
So, code search and debugging of Chromium can/should be fast enough, especially with VS 2022. I suspect that the slowdowns that you are seeing are related to Intellisense and project loading. If you generate project files (the --ide=vs option to gn gen) then loading these project files and parsing all of their dependencies can be very expensive, in RAM and CPU.
Personally I don't use these generated project files. I use VsChromium and code search to navigate the code and I use a debug-only project (see "Using Visual Studio without Intellisense"
here). If you do use generated project files it is important to filter down the list because 9,000 project files is unwieldy.
I hope that this information helps set expectations. Chromium development with Visual Studio can be fast, but it is definitely possible to overwhelm your system.
P.S. You said that your RAM is 89% full, but it's not clear what that means. The OS tries to use all available memory for disk cache so it is quite common to have only ~1% of memory "free" while having 60% or more of memory "available". The Windows Task Manager's performance tab has a memory section which has multiple memory usage numbers and these standardized numbers are easier for others to interpret than whatever tool you are using. Memory is complicated.