AP article on stress prostatitis
Mcapstone
Lee Robinette DVM was interviewed on Tuesday of this week by an
Associated Press reporter at the Experimental Biology 99 meeting in Washington,
DC concerning some research he presented at the meeting concerning the
relationship between stress and prostatitis in rats. She followed up with
Dr. Nyberg at NIH and the report she generated can be found on the internet
at:
http://www.cnn.com/HEALTH/9904/23/prostates.stress.ap/index.html
Anonymous
Superb posting, Brad!
You may also be interested in this work, from :
http://www.shef.ac.uk/uni/academic/A-C/csi/1997/PIR2.HTML
Prolactin receptors in the prostate
[In collaboration with Dr M. Nevalainen, University of
Turku, Finland]
Both the long and short form prolactin receptors have been
demonstrated in the glandular secretory epithelium of the
lateral and dorsal prostate of the rat. Expression of the
receptor gene(s) appears to be differentially controlled in
the dorsal and lateral prostates with the long form
regulated in a tissue specific manner by testosterone,
prolactin and estrogen whilst the short form showed only a
modest response. The studies have shown for the first time
that human prostate has a short form prolactin receptor as
well as a long form. Furthermore the epithelial cells were
found to produce prolactin suggesting that, as well as a
systemic source of the hormone, there is a tissue
paracrine/autocrine system acting in the prostate, which may
have implications for prostate cancer progression since
prolactin increases epithelial cell DNA synthesis.
--------------------------
More on prolactin:
THE MECHANISMS OF THE EFFECTS OF PROLACTIN ON PROSTATE:
http://www.utu.fi/research/tgsbs/studabstr/tahonabs.html
From the Mayo Clinic - Too Much Prolactin:
http://www.mayohealth.org/mayo/askphys/qa970815.htm
Yale Research:
http://www.med.yale.edu/cmphysiol/dannies.htm
NIDDK on Prolactinoma:
http://www.niddk.nih.gov/health/endo/pubs/prolact/prolact.htm
Chronic Prostatitis and Sinusitis, CFS / CFIDS, prolactin:
http://www.geocities.com/HotSprings/6028/perpet.htm
Some thoughts from me.....
1) I correlate the onset of my CP to *severe* work stress
and overwork. I am type 'A' (as if you couldn't guess).
2) Stress has a definite effect on the immune system - I
think that that is accepted science now (see my other
story posted today on the stress-illness link).
3) I find it interesting that prolactin in men is
associated with decreased sex drive (a problem I
have definitely noticed).
4) The alternative medicine people have this advice:
Regularly take B vitamins, vitamin C, calcium,
and magnesium. These vitamins help regulate
the production of prostaglandin E, which in turn
slows down prolactin activity. [I find Calcium
quite helpful, BTW]
5) For men with hyperprolactinemia, bromocriptine therapy
often is effective in normalizing the prolactin level
and improving sexual function.
[ http://www.thepillbox.com/impotence/impotence.htm ]
Daniel Shoskes MD
Anonymous <nob...@replay.com> wrote:
>
> Prolactin receptors in the prostate
>
etc
I have checked Prolactin levels in about 50 men with CP because of its
potential effects on libido and the whole prolactin receptor/BPH issue. Never
found a single patient with an abnormal value. Doesn't mean that something
isn't happening at the receptor level, but systemically there seems to be no
difference.
Daniel Shoskes MD
UCLA
http://www.ben2.ucla.edu/~dshoskes
Institute for Male Urology
http://www.urol
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