Do you have a particular reason to use python+cgi with apache? Having set up a moderately complicated website which, in retrospect, I would consider to be the 'wrong' or 'unnecessarily difficult' way, I would recommend you look at using one of the popular python web frame works (Django being my personal favorite).
However, with that suggestion in mind, if you insist on doing things the hard way here's what you dump into your /etc/<whatever redhat calls apache>/sites-enabled/000-default file:
<Directory /var/www/cgi-bin>
Options +ExecCGI
AddHandler cgi-script pl cgi
</Directory>
I don't know that the 'pl' does anything useful there, and the /var/www/cgi-bin folder is where you place your cgi scripts.
Good luck.