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Type-1 Diabetes Clinical Trials News
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joshua levy
Sep 6
Avotres Announces Results from a Phase-I Trial of AVT001
This blog posting reports on the results of Avotres recent phase-I clinical trial into AVT001 and the
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Avotres Announces Results from a Phase-I Trial of AVT001
This blog posting reports on the results of Avotres recent phase-I clinical trial into AVT001 and the
Sep 6
joshua levy
May 16
Diamyd’s GABA-Based Remygen® Unsuccessful in Phase 1 Clinical Trial
This clinical trial tested whether long-term daily treatment with Remygen®, an oral drug developed by
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Diamyd’s GABA-Based Remygen® Unsuccessful in Phase 1 Clinical Trial
This clinical trial tested whether long-term daily treatment with Remygen®, an oral drug developed by
May 16
joshua levy
May 8
Changes to My Blogging: AI
I'm going to start using generative AI (what people call "chatbot" technology) to help
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Changes to My Blogging: AI
I'm going to start using generative AI (what people call "chatbot" technology) to help
May 8
joshua levy
Apr 25
Sana Biotechnology Reports First Results For Islet Transplants Without Immunosuppression
This blog post reports on some news that I consider exciting, for at least two different reasons:
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Sana Biotechnology Reports First Results For Islet Transplants Without Immunosuppression
This blog post reports on some news that I consider exciting, for at least two different reasons:
Apr 25
joshua levy
Mar 18
TIXIMED Starts a Phase 1 Study of TIX100
TIX100 is a protein which inhibits the action of TIXNP (thioredoxin-interacting protein). It is being
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TIXIMED Starts a Phase 1 Study of TIX100
TIX100 is a protein which inhibits the action of TIXNP (thioredoxin-interacting protein). It is being
Mar 18
joshua levy
Mar 7
Combination of Harmine and GLP-1RA Completes Phase-I Clinical Trial (In Healthy People)
This is the most fun I have had writing a blog in a long time. It is not often I can blog about
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Combination of Harmine and GLP-1RA Completes Phase-I Clinical Trial (In Healthy People)
This is the most fun I have had writing a blog in a long time. It is not often I can blog about
Mar 7
joshua levy
Jan 31
Denosumab Starts A Phase-I Trial In People With Established T1D
Denosumab is a monoclonal antibody, which is already approved for several bone related diseases and
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Denosumab Starts A Phase-I Trial In People With Established T1D
Denosumab is a monoclonal antibody, which is already approved for several bone related diseases and
Jan 31
joshua levy
Jan 19
What To Watch In 2025
Last year, at the start of the year, I published a blog of four research projects I was looking
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What To Watch In 2025
Last year, at the start of the year, I published a blog of four research projects I was looking
Jan 19
joshua levy
12/31/24
JDRF Funding for a Cure 2024
Normally, sometime in October, I write a summary of all the clinical trials funded by JDRF. However,
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JDRF Funding for a Cure 2024
Normally, sometime in October, I write a summary of all the clinical trials funded by JDRF. However,
12/31/24
joshua levy
12/23/24
Fenofibrate Is Unsuccessful In A Phase-IIΔ Trial In Honeymooners
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
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Fenofibrate Is Unsuccessful In A Phase-IIΔ Trial In Honeymooners
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
12/23/24
joshua levy
11/19/24
Encellin Starts a Phase-I Trial of ENC-201-CED (Encapsulated Beta Cells)
The company Encellin has started a Phase-I clinical trial to test ENC-201-CED an encapsulated beta
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Encellin Starts a Phase-I Trial of ENC-201-CED (Encapsulated Beta Cells)
The company Encellin has started a Phase-I clinical trial to test ENC-201-CED an encapsulated beta
11/19/24
joshua levy
11/8/24
Frexalimab Starts A Phase-IIΔ Clinical Trial (FABULINUS)
There are two good reasons to test Frexalimab as a cure or treatment for Type-1 Diabetes (T1D). The
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Frexalimab Starts A Phase-IIΔ Clinical Trial (FABULINUS)
There are two good reasons to test Frexalimab as a cure or treatment for Type-1 Diabetes (T1D). The
11/8/24
joshua levy
10/6/24
The full story on "Stem cells reverse woman’s diabetes — a world first"
If you've been reading news recently you might have seen headlines like these: Stem cells reverse
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The full story on "Stem cells reverse woman’s diabetes — a world first"
If you've been reading news recently you might have seen headlines like these: Stem cells reverse
10/6/24
joshua levy
8/18/24
Combo of Rituximab and Abatacept Starts a Phase-II In Honeymooners (T1D RELAY)
Rituximab is FDA-approved to treat several autoimmune diseases, including Rheumatoid Arthritis (RA).
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Combo of Rituximab and Abatacept Starts a Phase-II In Honeymooners (T1D RELAY)
Rituximab is FDA-approved to treat several autoimmune diseases, including Rheumatoid Arthritis (RA).
8/18/24
joshua levy
7/16/24
Abrocitinib and Ritlecitinib Start A Phase-IIΔ Clinical Trail in Honeymooners (JAKPOT)
(Note: JAKPOT is a name of at least two different clinical trials. If you are reading about a French
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Abrocitinib and Ritlecitinib Start A Phase-IIΔ Clinical Trail in Honeymooners (JAKPOT)
(Note: JAKPOT is a name of at least two different clinical trials. If you are reading about a French
7/16/24
joshua levy
6/4/24
BMF-219 Starts a Phase-IIΔ
BMF-219 is a drug that inhibits Menin, a protein. Menin's functions in cells are not fully
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BMF-219 Starts a Phase-IIΔ
BMF-219 is a drug that inhibits Menin, a protein. Menin's functions in cells are not fully
6/4/24
joshua levy
5/1/24
Fenofibrate Starts A Phase-IIΔ Trial
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
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Fenofibrate Starts A Phase-IIΔ Trial
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
5/1/24
joshua levy
4/26/24
Siplizumab Starts Two Trials in Honeymoon T1D (DESIGNATE and STRIDE)
Siplizumab (MEDI-507, TCD601) is an monoclonal antibody which targets CD2 cells in the immune system.
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Siplizumab Starts Two Trials in Honeymoon T1D (DESIGNATE and STRIDE)
Siplizumab (MEDI-507, TCD601) is an monoclonal antibody which targets CD2 cells in the immune system.
4/26/24
joshua levy
4/12/24
Why I Don't Blog On How To Vote For T1D (part 1)
This whole blog posting is very US (and US politics) focused, but the issues are similar in other
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Why I Don't Blog On How To Vote For T1D (part 1)
This whole blog posting is very US (and US politics) focused, but the issues are similar in other
4/12/24
joshua levy
3/22/24
New Blog: Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People
Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People My previous blog posting:
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New Blog: Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People
Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People My previous blog posting:
3/22/24
joshua levy
3/8/24
Levicure's Combination Therapy
Levicure is a startup which is currently raising money to fund a phase-II trial for a combination
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Levicure's Combination Therapy
Levicure is a startup which is currently raising money to fund a phase-II trial for a combination
3/8/24
joshua levy
1/30/24
Results from a Phase-IIΔ Trial of Pleconaril and Ribavirin
This clinical trial represents an attack on T1D slightly different than anything I've blogged on
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Results from a Phase-IIΔ Trial of Pleconaril and Ribavirin
This clinical trial represents an attack on T1D slightly different than anything I've blogged on
1/30/24
joshua levy
1/22/24
Results From A Phase-IIΔ Baricitinib (Olumiant)
Baricitinib (trade name Olumiant) is a drug which targets the immune system, and is already approved
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Results From A Phase-IIΔ Baricitinib (Olumiant)
Baricitinib (trade name Olumiant) is a drug which targets the immune system, and is already approved
1/22/24
joshua levy
1/6/24
What To Watch In 2024
At the start of a new year, some bloggers write a posting on the year that was, and a some write a
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What To Watch In 2024
At the start of a new year, some bloggers write a posting on the year that was, and a some write a
1/6/24
joshua levy
12/24/23
Diamyd Update
This is my first update on the Diamyd company in many, many years. It is focused on their DIAGNODE-3
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Diamyd Update
This is my first update on the Diamyd company in many, many years. It is focused on their DIAGNODE-3
12/24/23
joshua levy
12/16/23
Islet Cell Transplantation Clinical Trails
In this blog I'm going to report on three different clinical trials involving transplantation.
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Islet Cell Transplantation Clinical Trails
In this blog I'm going to report on three different clinical trials involving transplantation.
12/16/23
joshua levy
11/28/23
Teplizumab/Tzield Reports Results From A Phase-III in Honeymooners (PROTECT)
Teplizumab (sold as Tzield) was recently approved for use in people at-risk of diagnosis for T1D. At
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Teplizumab/Tzield Reports Results From A Phase-III in Honeymooners (PROTECT)
Teplizumab (sold as Tzield) was recently approved for use in people at-risk of diagnosis for T1D. At
11/28/23
joshua levy
11/11/23
JDRF Funding for a Cure 2023
In the US, we are in the "Walking Season" when JDRF (Juvenile Diabetes Research Foundation)
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JDRF Funding for a Cure 2023
In the US, we are in the "Walking Season" when JDRF (Juvenile Diabetes Research Foundation)
11/11/23
joshua levy
10/9/23
DFMO Starts A Phase-II Clinical Trial (TADPOL)
Difluoromethylornithine (DFMO), also known as Eflornithine, is FDA approved since 1990 as an
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DFMO Starts A Phase-II Clinical Trial (TADPOL)
Difluoromethylornithine (DFMO), also known as Eflornithine, is FDA approved since 1990 as an
10/9/23
joshua levy
9/21/23
Strong Results from a Pilot Study of Semaglutide in Adult Honeymooners
I've been blogging on research aimed at curing type-1 diabetes for over 15 years, and in that
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Strong Results from a Pilot Study of Semaglutide in Adult Honeymooners
I've been blogging on research aimed at curing type-1 diabetes for over 15 years, and in that
9/21/23