b) You can only send messages directly to users who are following you
(opt-in, to prevent spam). You can post an @reply to that user
whether or not they're following you, though. Doing so for marketing
purposes is a good way to annoy people enough that they block you and
signal to us that you're a spammer, though.
If you want to find people talking about your institution, check out
our new Search API: http://search.twitter.com/api
--
Alex Payne
http://twitter.com/al3x