TODAY!!! Campus Stem Cell Lab meeting, Tuesday, March 19
Sue Gilbert
Our next talk this semester will be today, Tuesday, March 19, and will start at noon promptly. I apologize for the lateness of this notice. I really thought I had taken care of it last week.
We will continue to meet in The Wisconsin Institutes of Discovery (WID) for most of the talks. We will be meeting in the H.F. Deluca Forum in the Town Center on the first floor. Please ask at Information Desk if you are unsure where to go. We will continue to provide sandwiches and chips starting at 11:50am (water will be provided but if you want something else to drink please bring your own.)
Date: Tuesday, March 19
Speaker: Sam Gubbels, Assistant Professor, Otolaryngology
Title: Inner Ear Progenitor Cell Generation from Human Pluripotent Stem Cells
Abstract: Hearing loss is the most common disability in industrialized countries. Hearing loss is due to loss or dysfunction of the hair cells of the inner ear sensory epithelium. Hair cells cannot spontaneously regenerate in mammals, which leads to the permanency that typifies most cases of hearing loss. Mouse pluripotent stem cells can be used to generate functional hair cells in vitro however there are a paucity of reports of the use of human pluripotent stem cells for the same purpose. In this lecture we will discuss the generation of a population of inner ear (otic) - like progenitor cells from human pluripotent stem cells upon neural differentiation in vitro. Otic-like progenitors from alongside developing neural progenitor cells and express a panel of gene and protein markers indicative of an inner ear fate. Furthermore, the sequence of expression of otic markers occurs in a pattern that appears to recapitulate that seen during normal mammalian inner ear development. In addition, modifications in an established neural differentiation paradigm enrich this population of otic-like progenitor cells. Ongoing studies in our laboratory focusing on long-term differentiation of otic progenitor-like cells to a hair cell fate and inner ear transplantation will be discussed.
Reminder: If you are talking this Seminar Series for credit, please check in with Sue Gilbert at the back of the room.
There will be NO talk on Tuesday, March 26 since it will be Spring Break! Have a great vacation if you can get away.
Next talk: On Tuesday, April 2, our speaker will be Tapas Nayak, Postdoctoral Research Associate (Cai lab), Radiology, Medical Physics and Biomedical Engineering, who will be speaking on “Tissue Engineering with Carbon Nanomaterials and Stem Cells” This talk will be in Wisconsin Institutes of Discovery (WID), H.F. Deluca Forum in the Town Center on the first floor, and will include sandwiches.
A list of the talks for the semester is found at:
http://stemcells.wisc.edu/node/246
Thank you for supporting this venue for the sharing of information..
Sue Gilbert
Office Operations Associate
Stem Cell and Regenerative Medicine Center
5036 WIMR
1111 Highland Avenue
Madison, WI 53705-2275
Tel: (608) 263-2982
FAX: (608) 263-5267
"The science fiction of yesterday happens to be a lot of the medicine of today"