Campus Stem Cell Lab meeting, Tuesday, May 7
Sue Gilbert
Our last talk this semester will be on Tuesday, May 7, and will start at noon promptly. We look forward to another wonderful visiting speaker, Samuel Rabkin from Harvard Medical School.
We will continue to meet in The Wisconsin Institutes of Discovery (WID) for most of the talks. We will be meeting in the H.F. Deluca Forum in the Town Center on the first floor. Please ask at Information Desk if you are unsure where to go. We will continue to provide sandwiches and chips starting at 11:50am (water will be provided but if you want something else to drink please bring your own.)
Date: Tuesday, May 7
Title: Cancer Stem Cells in Glioblastoma
Abstract: Cancer stem cells are posited to be a subpopulation of transformed cells in tumors with stem-like properties; self-renewal and differentiation into multiple lineages. They are thought to be important in cancer progression, tumor heterogeneity, and response to therapy. Glioblastoma is the most common primary brain tumor in adults and the prognosis for patients is exceedingly poor. Glioblastoma is one of the solid tumors where cancer stem cells have been isolated. We have been characterizing glioblastoma stem cells (GSCs), isolated as sphere cultures from patient tumor specimens. The GSCs efficiently form tumor xenografts in the brains of immune-deficient mice that are morphologically heterogeneous and histologically recapitulate the phenotype of the corresponding patient's tumor. They have genetic and epigenetic features that distinguish them from the bulk serum-cultured tumor cells, which are only weakly tumorigenic. Thus, GSCs provide highly representative models for the development of cancer therapeutics.
Please post the attached flyer wherever appropriate and pass this information on to those who might be interested.
Reminder: If you are talking this Seminar Series for credit, please check in with Sue Gilbert at the back of the room.
Next talk: We will be on hiatus all summer and will be back in September. We’re still looking for speakers so please contact me at sggi...@wisc.edu if you are interested in speaking as part of this series.
Thank you for supporting this venue for the sharing of information.
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Sue Gilbert
Office Operations Associate
Stem Cell and Regenerative Medicine Center
5036 WIMR
1111 Highland Avenue
Madison, WI 53705-2275
Tel: (608) 263-2982
FAX: (608) 263-5267
"The science fiction of yesterday happens to be a lot of the medicine of today"