Israeli Develops Revolutionary Wound Dressing
mos...@mm.huji.ac.il
by Hillel Fende
(IsraelNN.com) A revolutionary, dissolvable wound dressing developed at Tel
Aviv University could help reduce deaths caused by burn-related infections.
ScienceDaily.com reports that currently, 70% of those with severe burns die
from related infections. Prof. Meital Zilberman of Tel Aviv University's
Department of Biomedical Engineering has developed a new wound dressing that
is filled with antibiotics and other healing agents, and that dissolves when
the wound is healed.
The dressing is based on fibers that Prof. Zilberman engineered. A study
published in the Journal of Biomedical Materials Research shows that the new
dressing can eradicate infection-causing bacteria after only two days.
"We've developed the first wound dressing that both releases antibiotic
drugs and biodegrades in a controlled manner," Prof. Zilberman said. "It
solves current mechanical and physical limitations in wound-dressing
techniques, and gives physicians a new and more effective platform for
treating burns and bedsores."
The ScienceDaily report explains that Prof. Zilberman designed the dressing
to mimic skin and the way it protects the body. "Wound dressings must
maintain a certain level of moisture while acting as a shield," she
explained. "Like skin, they must also enable fluids from the wound to leave
the infected tissue at a certain rate. It can't be too fast or too slow. If
too fast, the wound will dry out and it won't heal properly. If too slow,
there's a real risk of increased contamination."
The dressing thus combines positive mechanical and physical properties with
what medical researchers call "a desired release profile of antibiotics."
Prof. Zilberman is now starting the early stages of clinical trials on
animal models. So far, her wound dressing has passed physical and mechanical
tests in vitro and in bacterial inhibition tests in the laboratory. She is
also seeking a strategic partner to co-develop the research and take it to
the commercial stage.
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