Murder and the Strains Game, Part II, Quest and Yale and Lou Magnarelli

[Mort Zuckerman]

Date: Aug 7, 2008 7:13 AM

http://www.ncbi.nlm.nih.gov/pubmed/8788993?ordinalpos=30&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


Use of recombinant antigens of Borrelia burgdorferi in serologic tests
for diagnosis
of lyme borreliosis.
Magnarelli LA, Fikrig E, Padula SJ, Anderson JF, Flavell RA.

Department of Entomology, Connecticut Agricultural Experiment Station,
New Haven
06504, USA.

Recombinant antigens of outer surface proteins (Osps) OspA, OspB,
OspC, OspE, and
OspF of Borrelia burgdorferi sensu stricto and of p41-G, an antigenic
region of
flagellin of this spirochete, were tested with human sera in class-
specific and
polyvalent enzyme-linked immunosorbent assays (ELISAs). In analyses
for immunoglobulin
M (IgM) antibodies, 18 (85.7%) of 21 serum samples from persons who
had been diagnosed
as having Lyme borreliosis on the basis of the presence of erythema
migrans reacted
positively in ELISAs with one or more Osp antigens or the p41-G
antigen. ***Eleven
serum samples contained antibodies to OspC antigen, and of these, six
also reacted
to the p41-G antigen and to one or more of the other recombinant
antigens. The remaining
five serum samples reacted solely to OspC (n = 4)**** or to OspC plus
OspA and
OspE without reactivity to p41-G (n = 1). In analyses for IgG
antibodies, seropositivity
was comparable to that of IgM analyses and was marked by predominant
reactivity
to p41-G, OspC, and OspF. Similarly, all 21 serum samples were
positive in polyvalent
and class-specific ELISAs with whole-cell B. burgdorferi. Minor cross-
reactivity
was noted when sera from persons who had syphilis, periodontitis or
other oral infections,
or rheumatoid arthritis were tested with OspC, OspE, OspF, and p41-G.
With relatively
high degrees of specificity, ELISAs with recombinant antigens,
particularly OspC
and p41-G, can help to confirm B. burgdorferi infections.


There you have it. Everybody with early Lyme
has anybodies to OspC, but there is no OspC in
strain B31- the strain used by Quest (to this day, that
is, STILL) and SmithKline to assay LYMErix victims.

Not that any bands would be detected anyway
since the blots were unreadable:
http://www.actionlyme.org/DICKSON_FDA_SUBMISSION_FULL.htm

So, SmithKline and Schoen simply lied to the FDA about
the outcomes of LYMErix.

The State of Corrupticut has a contract with Quest
to perform all our Lyme testing.

Jodi Rell does not care, and this is certain, vbecause
I already informed her office about Quest and their
fraudulent testing. She went ahead with the contract
anyway.

You do not hear these kinds of complaints from the Pat
Smith gang
http://www.lymediseaseassocation.org
down there in Greenwich, because the Steopford
wives would prefer to fulfill the assertion that we're all
airheaded housewives looking for attention.

I am surprised that Pam Weintraub, the writer, did not inform
Pat Smith of this problem with Quest and OspC.

I hear nothing about it from the peanut gallery down there
in Greenwich.


Kathleen M. Dickson
http://www.actionlyme.org


-----Original Message-----
>From: Kathleen <janmu...@earthlink.net>

>Sent: Aug 7, 2008 6:48 AM
>Subject: Murder and the Strains Game
>
>Establish that OspC is associated with brain invasion:
>
>http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&DbFrom=pubmed&Cmd=Link&LinkName=pubmed_pubmed&LinkReadableName=Related%20Articles&IdsFromResult=9234797&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&log$=relatedarticles&logdbfrom=pubmed
>
>http://www.actionlyme.org/JohnDunn_Brookhaven.htm
>==========================
>
>Imugen Report Form
>http://www.actionlyme.org/IMUGEN_FORM_FRG.htm
>showing the use of strains G39/40 and FRG, after the Dearborn Conference
>http://www.actionlyme.org/Dearborn_Who_Approved.htm
>where it was stated which strains should be used. Quest Labs uses strain B31
which has no OspC or band 23 in it. See Chapter 1 of CRYME DISEASE,
>http://www.actionlyme.org/CRYMEDISEASE_CHP1.htm
>where we see several people from Yale and UConn try to develop a Lyme assay
with OspC from strain 2591 and see also all the RICO movies,
>http://www.actionlyme.org/YOUTUBEVIDEOS.htm
>especially the PATENTS movie. This cabal is playing a strains game.
>
>Quest bought the Lyme Western Blot testing from SmithKline, who used strain
B31 to Western Blot (unreadable anyway) people in the LYMErix trial.
>http://www.actionlyme.org/DICKSON_FDA_SUBMISSION_FULL.htm
>Quest to this day is still using strain B31, which has no OspC in it. OspC
is associated with brain invasion. SmithKline and Kaiser-Permanente
are in cahoots
with the www.aldf.com cabal.
>http://www.actionlyme.org/JUNE_13_2005_LETTER_TO_SPITZER.htm
>http://www.actionlyme.org/ALDF_BOARD.htm
>Although the three people who allegedly established the aldf.com (Gary Wormser,
John J. Connolly, and Durland Fish)
>http://www.actionlyme.org/CONNOLLY_FISH_WEINSTEIN.htm
>are not NIH staff or CDC officers, NIH and CDC staff are deeply involved in
this criminal entity with SKB (GSK) and Kaiser, to not detect
neurologic Lyme or
the immune suppression outcomes (the New Great Imitator outcomes).
>http://www.actionlyme.org/CHP_9_IDSA_REVIEWS.htm
>We think NIH's Crazy Eddie McSweegan (this week's topic) was the fourth
founding partner of the www.adlf.com, based on what he did (trashing
the US Navy)
>http://www.actionlyme.org/GOLDWATER_LETTER.htm
>to insert himself into the top of the NIH's "Lyme Program," in
order to be in charge of all the funding, to give all the money to his
criminally
insane friends.
>=========================
>
>These assholes killed far more people than Bruce Ivins, if Ivins did it.
>
>And even if Ivins did do it, we need to look at what kind of grandiose thinking
goes
>into deciding for himself that he had to kill a few Americans in order to vaccinate
the
>rest.
>
>Get it?
>
>What kind of thinking goes into rearranging the definition of the disease in
>order to advance one's personal income, arranging to commit the fraud with
>Kaiser Permanente, trash all the New Great Imitator victims (including
>the deadly ALS version of Lyme) and activists.
>
>Comparatively speaking, Bruce Ivins was nowhere near as mentally ill
>as McSweegan, Fish, Shapiro and Schoen.
>
>Now that we know Lyme is a crime, get a copy of Under Our Skin
>and watch their expression as they lie. It's very subtle. They're
>telling themselves, even when they lie under oath, that "Lyme Disease"
>is that disease with no brain or fatigue signs, as explained by Mark
>Klempner and Gary Wormser, here:
>http://www.journals.uchicago.edu/doi/pdf/10.1086/432733
>
>"Lyme Disease" is only an arthritis in a knee. That is the
>only kind of Lyme that can be detected with the Steere/Dearborn
>method. Go back and look at the graphics in the Steere
>Chapter of Cryme Disease. Look at the "receiver operator
>characteristics."
>http://www.actionlyme.org/CRYMEDISEASE_CHP3_B.htm
>
>There is no such criterion for validating a method. A method
>validation includes HOW RELIABLY CAN YOU DETECT THE LOWEST CONCENTRATION
>OF *A* SPECIFIC ANALYTE IN A MIX.
>http://www.fda.gov/CDER/GUIDANCE/4252fnl.htm
>
>1. Lower Limit of Quantification (LLOQ)
>
>The lowest standard on the calibration curve should be accepted as the limit
of quantification if the following conditions are met: ...
>
>
>==========
>So there you have it. Steere designed the disease around the
>vaccine. They said the only way you could have a disease was if
>there was inflammation, when the crux of the seriousness of the
>disease was the immune suppression/dysregulation outcomes.
>
>Did the bad guys know this?
>
>OF COURSE, they knew it in 1989:
>http://www.actionlyme.org/CHP_9_IDSA_REVIEWS.htm
>===================
>Shapiro and Sigal lying to the press:
>
>http://www.geocities.com/kmdickson0308/lyme-dilemma.html
>
>http://www.geocities.com/kmdickson0308/1-4.txt
>
>4. Sigal and Shapiro Spinning Lyme for the Press
>
>From the Life on Earth Series: 9/15/00
>(Linked or enclosed)
>
>SHAPIRO: What some people would have you believe is that there are two
>different diseases.
>
>SHAPIRO: Somehow, for that form of the disease, antibiotics are
>effective. They do fine. But then there's some other form of the
>disease which is, you can't put your hand around it. They don't have
>objective findings of inflammation, which is the way bacteria cause
>disease.
>
>TOOMEY: What these patients do have are symptoms that doctors call
>nonspecific. They span a broad spectrum. Emotional problems, as in the
>case of Lisa's daughter; or fatigue, muscle pains, depression. Doctor
>Shapiro helped write the Lyme treatment guidelines put out by the
>Infectious Diseases Society of America. Guidelines that state even the
>most advanced cases of infection can be eradicated with two months of
>oral or intravenous antibiotics. But for the patients with these
>ongoing, nonspecific symptoms, the maximum treatment didn't seem to
>work.
>
>SHAPIRO: They would have you believe that form of the disease, somehow
>this is, the bacteria knows to act differently and it doesn't respond to
>antibiotics in this sense. It really doesn't make any sense.
>
>SIGAL: Nobody has ever found a Borrelia Burgdorfer that is resistant to
>the standard antibiotics that are used in the treatment of Lyme Disease.
>Which I think really
>pokes a major league hole in the theory that what you've got is you need
>more antibiotics because you've made a super-bug.
>
>================================================
>
>Time to call Grassley, I guess.
>
>Zerhouni is clearly not doing anything about this, and you all have seen him
>copied in here for months. We want our money back for his salary, too.
>
>
>Kathleen M. Dickson
>