JAMA tells a funny story
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Mort Zuckerman
Feb 10, 2009, 6:22:03 PM2/10/09
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Subject: JAMA tells a funny story
Date: Feb 10, 2009 6:21 PM
http://jama.ama-assn.org/cgi/content/full/301/6/665
"The case exemplifies the politicization of health policy, with
elected officials advocating for health policies against the weight of
scientific evidence."
=================================
Oh.
Ya mean there's someone besides IDSA, the US Military,
and the CDC who has proven scientifically that spirochetes
are not permanent infections that go into latency... like
chicken pox and shingles?
http://www.actionlyme.org/BRAIN_PERMANENT.htm
http://www.actionlyme.org/RICOCHRON.htm
*1) In 1975 there was apparently an international conference on
spirochetal diseases. The following year the conference was
summarized in book form, by Russell Johnson and was entitled, The
Biology of Parasitic Spirochetes.
Dr. Jay Sanford of the "Uniformed Services Military Hospital" in
Bethesda, Maryland, reported:
"The ability of the borrelia, especially tick-borne
strains to persist in the brain and in the eye after treatment with
arsenic or with penicillin or even after apparent cure is well known
(1). The persistence of treponemes after treatment of syphilis is a
major area which currently requires additional study (3,5,10,11)." -
Jay Sanford, US Military Hospital, Bethesda, MD
Russell Johnson later published for the 1989 IDSA Reviews, special
supplement on Lyme and spirochetal diseases that: "Although
spirochetes can often be detected in culture media after 3 weeks of
culture, some isolates may not be visible for several months."
IDSA says we need to culture these suckers for several months.
Did Mark Klempner do that in his bogus long term treatment "study?"
NO.
=================================================================
2) http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=373079&blobtype=pdf
By CDC Officer Alan Barbour, in 1986, The Biology of Borrelia
Species:
"The propensity for borrelia to go to the brain of infected
mammals suggests that the relationship between these spirochetes and
neural tissues is not trivial. Further study of this attraction and
the interaction that follows may reveal the basis for the significant
nerve and brain involvement in Lyme borreliosis"--
This is self-explanatory. We have previously seen that rodent
brains so reliably were a home for spirochetes that they were actually
the culture media. We also acknowledge that ceftriaxone for brain
diseases was a treatment IDSA themselves used and offered and still
use, so Lyme must not be a self-limiting knee disease as Allen Steere
and Yale's Steven Malawista claim.
And here we have in the same CDC officer's 1986 report that there
are, gasp, "gemma:"
[You want to GO HERE for other older references published
before the Great Whore of Medicine, Allen Steere emerged onto the
scene]
=================================================================
3) Russell Johnson's patent for the very first Lyme vaccine
US PATENT 4,721,617
"The chronic forms of the disease such as arthritis (joint
involvement), acrodermatitis chronica atrophicans (skin involvement),
and Bannwart's syndrome (neurological involvement) may last for months
to years and are associated with the persistence of the spirochete. A
case of maternal-fetal transmission of B. burgdorferi resulting in
neonatal death has been reported. Domestic animals such as the dog
also develop arthritis and lameness to this tick-borne infection. For
every symptomatic infection, there is at least one asymptomatic
infection. Lyme disease is presently the most commonly reported tick-
borne disease in the United States." --
The patent also says:
"The infection may be treated at any time with antibiotics
such as penicillin, erythromycin, tetracycline, and ceftriaxone. Once
infection has occurred, however, the drugs may not purge the host of
the spirochete but may only act to control the chronic forms of the
disease. Complications such as arthritis and fatigue may continue for
several years after diagnosis and treatment."
=============================================================
4) At the time of the writing of this book, CDC officer Alan
Barbour has on his website, the following statement:
"We are taking a multi-discipline approach, including methods
of genetics, cell biology, and immunology, to study in depth two
spirochetal diseases: Lyme disease and relapsing fever. These tick-
borne infections are notable for multiphasic antigenic variation
through DNA recombinations in the case of relapsing fever, the
occurrence of chronic arthritis in the case of Lyme disease, and
invasion of and persistence in the brain in the case of both
diseases. ---Alan Barbour
============================================================
*5) In 1994 Alan Steere and other published a report entitled:
http://www.annals.org/cgi/content/full/121/8/560
The Long-Term Clinical Outcomes of Lyme Disease: A Population-
based Retrospective Cohort Study
right arrow Nancy A. Shadick; Charlotte B. Phillips; Eric L.
Logigian; Allen C. Steere; Richard F. Kaplan; Victor P. Berardi; Paul
H. Duray; Martin G. Larson; Elizabeth A. Wright; Katherine S.
Ginsburg*; Jeffrey N. Katz; and Matthew H. Liang
15 October 1994 | Volume 121 Issue 8 | Pages 560-567
In that report:
"Patient 12 had had high fever, meningeal symptoms, and
subsequent arthritis in 1982. She was noted to have a positive
serologic test result for Lyme disease 4 years later and was treated
with 2 weeks of parenteral penicillin. She later developed a
progressive speech disorder, bradykinesia, and abnormal ocular motor
function. Magnetic resonance imaging of the brain showed scattered
white matter lesions in the hemispheres and pons, and she was
diagnosed with supranuclear palsy. Lumbar puncture showed no selective
concentration of antibody in the spinal fluid. Nevertheless, she was
re-treated with 2 weeks of parenteral ceftriaxone in 1989 that had no
effect on her neurologic symptoms. During the time of observation,
this patient died. At autopsy, lymphoid mononuclear cells were
observed surrounding the intracerebral vessels in one section. Using
Dieterle silver stain, a spirochete was present in the cortex and
another was exterior to a leptomeningeal vessel."
One of Steere's multiply-treated patients died anyway with
spirochetes in her brain. How amazing that that suddenly doesn't
happen any more, despite no new breakthroughs in antibiotic treatments
or their delivery.
The Primer's Shell Game is where these Lyme crooks use the
wrong DNA (or RNA) primers (they use the variable Osp primers instead
of the non-variable chromosomally encoded) to test Lyme victims.
These same crooks use the correct DNA primers when they want to find
Lyme or borrelia in ticks (to patent). It's a shell game. They all
know that all that they can use for treatment outcomes is non-variable
DNA or RNA.
Mark Klempner never reported his primers in his Chronic
Lyme "study," and he would not tell me, either, in an email
correspondence I had with him. Therefore, the Lyme crooks have never
validly reported on the presence of borrelia in humans, with the
exception of Gary Wormser's study of EMs in which he found 2/9
patients who had EM, who had been treated with antibiotics still had
spirochetes in their tissues. This data can be found on the HOW RICO
WILL BE CHARGED PAGE
- - -
Clin Microbiol Infect. 2008 Jul;14(7):653-8.
Comparison of PCR methods and culture for the detection of
Borrelia spp. in patients with erythema migrans.
http://www.ncbi.nlm.nih.gov/pubmed/18558937?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
Cerar T, Ruzić-Sabljić E, Glinsek U, Zore A, Strle F.
Institute of Microbiology and Immunology, Faculty of
Medicin, University of Ljubljana, Slovenia. tjasa...@mf.uni-lj.si
The sensitivities of two PCR assays and culture were
compared for the detection of Borrelia spp. in skin specimens of 150
patients with typical erythema migrans. In addition, the accuracy of
the methods for the identification of Borrelia spp. was compared by
analysing culture isolates and material obtained directly from skin
biopsy specimens. Borrelia burgdorferi sensu lato was isolated from 73
(49%) of 150 skin biopsy specimens. Using a nested PCR targeting the
rrf-rrl region and a PCR targeting the flagellin gene, 107 (71%) and
36 (24%) specimens, respectively, were positive. With both PCRs,
positive results were more frequent with culture-positive samples
(67/73 (92%) and 24/73 (33%) for the nested and flagellin PCRs,
respectively) than with culture-negative samples (40/77 (52%) and
12/77 (16%) for nested and flagellin PCR, respectively). Pulsed-field
gel electrophoresis after MluI restriction identified 69/73 (95%)
isolates, of which 58/69 (84%) were Borrelia afzelii and 11/69 (16%)
were Borrelia garinii. After MseI restriction of PCR products
amplified from the intergenic rrf-rrl region, B. afzelii was
identified in 73/107 (68%) samples, B. garinii in 22/107 (21%)
samples, and both species in 11/107 (10%) samples. The corresponding
results for culture-positive specimens were 41/69 (59%), 14/69 (20%),
and 7/69 (10%). Comparison of the results for specimens positive
according to both approaches revealed complete uniformity in 80% of
the cases. Overall, nested PCR was the most sensitive method for the
demonstration of Borrelia spp. in erythema migrans skin lesions,
followed by culture and PCR targeting the flagellin gene. The
congruence of identification results obtained by analyzing culture
isolates and material obtained directly from skin biopsies was
relatively high but incomplete.
The Borrelia Flagellin Master Prober: Picken, 1992:
http://jcm.asm.org/cgi/reprint/30/1/99?view=long&pmid=1734073
Burgdorferi is most similar to hermsii
Mark Klempner, in his fake long term retreatment study, did
not reveal which DNA primers he used to discover no-lyme in the CSF of
previously terated Lyme victims, even when asked directly. The NEJM
had no problem with Klempner not reporting his Methods and Materials
in the Methods and Materials section of his report.
http://content.nejm.org/cgi/reprint/345/2/85.pdf
Klempner states in his report that people who were positive
were excluded from the study because it would be unethical not to
treat patients who were DNA positive for Borrelia, and so they were
excluded from the start. We know of at least one patient who joined
Klempner's study because she/he was Borrelia burgdorferi DNA-positive.
For Klempner to claim publicly that there were no Bb DNA
positive patients at all, is research fraud.
Recall from the Russell Johnson Culturing article published in
the 1989 IDSA Reviews special supplement on Lyme and spirochetal
diseases, it could take months to regrow intact spirochetes in BSK
media from the cystic form:
===============================================================
*6, 7) In 1994 and in 1996, Steere and Nocton published a reports
of treatment failure and brain invasion using RNA and DNA methods and
they found treatment failed in a third of the patients with their OspA
primer sets. In the first report, in 1994, published in the New
England Journal of Medicine, that they used 4 primer sets. Three were
for the OspA gene (which we know undergoes antigenic variation and
therefore these are the wrong probes). The fourth set was for 16S RNA
intragenic spacer (remember now, for Borrelia burgdorferi, ignoring
all the other possibilities). These were rather valuable reports,
overall, since they prove that Allen Steere and the ALDF cabal is
saying something much different today about the what the disease
actually is (brain infection) and about treatment outcomes.
http://content.nejm.org/cgi/content/full/330/4/229
Detection of Borrelia burgdorferi DNA by polymerase chain reaction
in cerebrospinal
fluid in Lyme neuroborreliosis.
"of 73 patients with Lyme arthritis who were untreated or
treated with short courses of oral antibiotics before testing, 70 (96
percent) had positive PCR results. In contrast, of 19 patients who
received either parenteral antibiotics or long courses of oral
antibiotics, only 7 (37 percent) had positive test results after
treatment (P<0.001). In the 29 patients for whom serial samples were
available, all pretreatment samples were positive."
Self-explanatory.
About a third of the patients still had spirochetes in their knees
after antibiotic treatment.
- - - -
The following is not a treatment outcomes assessment, but merely
demonstrates that Allen Steere acknowledges the brain disease called
"chronic neuroborreliosis" and that he previously had proven with the
synovial fluid DNA post-treatment analysis, that treatment failed in a
third of the cases. As I do not have the full text of this report,
and the probes were not reported, I can't comment on whether or not
they were the correct ones. As the correct ones by this time had been
used by Gary Wormser and Robert Schoen when assessing tick bite
treatment outcomes and whether or not the spirochete missing the OspA-
B plasmid belonged to this new New England deer tick relapsing fever
group, respectively, we can guess that Allen Steere maybe knew which
primer probes to use: 16S and 23S RNA, but better from more from the
genera:
http://www.ncbi.nlm.nih.gov/pubmed/8769624
Detection of Borrelia burgdorferi DNA by polymerase chain
reaction in cerebrospinal fluid in Lyme neuroborreliosis.
: J Infect Dis. 1996 Sep;174(3):623-7.
Nocton JJ, Bloom BJ, Rutledge BJ, Persing DH, Logigian EL, Schmid
CH, Steere AC.
Division of Rheumatology/Immunology, New England Medical Center,
Boston, Massachusetts02111, USA.
A polymerase chain reaction (PCR) assay that detects Borrelia
burgdorferi DNA in cerebrospinal fluid (CSF) was evaluated as a
diagnostic test for acute or chronic Lyme neuroborreliosis. In one
laboratory, 102 samples were tested blindly, and 40 samples were
retested in a second laboratory. In the first laboratory, B.
burgdorferi DNA was detected in CSF samples in 6 (38%) of 16 patients
with acute neuroborreliosis, 11 (25%) of 44 with chronic
neuroborreliosis, and none of 42 samples from patients with other
illnesses. There was a significant correlation between PCR results and
the duration of previous intravenous antibiotic therapy. The overall
frequency of positive results was similar in the second laboratory,
but concordance between the laboratories and among primer-probe sets
was limited because many samples were positive with only one primer-
probe set. Thus, PCR testing can sometimes detect B. burgdorferi DNA
in CSF in patients with acute or chronic neuroborreliosis, but with
current methods, the sensitivity of the test is limited.
PMID: 8769624 [PubMed - indexed for MEDLINE]
Perhaps the best way to prove antibiotic efficacy is with monkeys
treated with ceftriaxone and then subject to the Mouse (monkey)
Infectivity Test.
=======================================================================
*8, 9)
As reported in the previous chapter, and in the introduction of
this one, Mark Klempner says the IV drug ceftriaxone, which is used
for meningitis (and not knee-only diseases), does not kill all the
spirochetes (click here for full text journal article)
"Fibroblasts protected B. burgdorferi for at least 14 days of
exposure to ceftriaxone. Mouse keratinocytes, HEp-2 cells, and Vero
cells but not Caco-2 cells showed the same protective effect. Thus,
several eukaryotic cell types provide the Lyme disease spirochete with
a protective environment contributing to its long-term survival." HERE
on Medline (same report as above)
Mark Klempner here describes a special nerve and brain
degrading enzyme, Matrix-metalloproteinase 130 that he found in
chronic Lyme patients. Be sure to read why he performed this study.
====================================================================
10) In 1999, Mark Klempner reported with Denise Huber at Tufts,
"Autoimmunity; Is is Me or Thee?"
http://www.nature.com/nm/journal/v5/n12/abs/nm1299_1346.html;jsessionid=47122A0C58C911613E8BDE31ED7C9609
Same report: Klempner reported that OspA or LYMErix could cause
brain disease as if that needs an explainer.
"T cells that react to OspA, OspC and p 22 epitopes also
recognize myelin basic protein, SST-R1m and IL-1R, respectively,
possibly leading to encephalopathy and radiculopathy..."
We're not too impressed with the T cell data to support that
hypothesis, but we are impressed with Mark Klempner's non-reporting
the possible association between OspA vaccination and brain damage,
since in 1999, LYMErix had come onto the market. We're also impressed
with the fact that in 2003 Mark Klempner said there was no such thing
as cognitive impairment associated with Lyme infection. We claim that
myelin has something to do with brains and nerves, and that the spinal
fluid was from whence Mark discovered the very special MMP-130.
NINDS' Roland Martin did not prove T cell autoimmunity, and so he
went home to Germany. Martin failed to prove that the Multiple
Sclerosis version of "Lyme Disease" is caused by T cell autoimmunity,
just as Allen Steere failed to find T cell autoimmunity was the cause
of the knee kind of Lyme. If Lyme-Knee and Lyme-Brain are not really
T cell autoimmunity diseases, then what are they ya think?
Read more about that on this page: 080515.htm
See Mark Klempner's nice flow chart (more detailed version,
HERE):
=======================================================================
*11) Yale Pathology and the Congenital Brain Infection of Newborn
Resulting in Death "The death of the newborn was probably due to
respiratory failure as a consequence of perinatal brain damage."
The child and mother were seronegative, they were treated, and
there was remarkably "no inflammation." Yale's Eugene Shapiro claimed
in PBS' Life on Earth Series that the only way you can have a disease
is if you have inflammation.
The baby died of congenital Lyme brain damage, anyway. This is
not the only such report, and they report on several babies who died
from congenital Lyme.
MORE HERE
==========================================================================
12) When trying to strike fear into the hearts of the New England
Munchausers, hypochondriacs, trophy-wives who co-suffer Viagra-deficit
syndrome, Fibrofemzalgiacs, "what I call Lyme Paranoia, "
antibiomaniacs, members of the "Lyme internet cult," and other
delusional newsgroup posters, Yale's Robert Schoen said about the
LYMErix vaccine:
http://www.annals.org/cgi/reprint/132/8/661.pdf
In late-stage disease [a disease now called Munchausen's by proxy,
etc], the central nervous system [which we know to be a complicating
variable and should be thrown out] may be involved. A new diagnostic
test [not ever to be used, since it is a scientifically valid marker
of real illness and we Lyme crooks never go there, preferring the
services of the professional, perpetual pee-pee whacking Voo-Dooists
of medicine, psychiatry] measuring glial fibrillary acidic protein in
the cerebrospinal fluid may prove to be a useful tool in measuring
such involvement.
"Oh," we say.
"My, my. A new disease for us bored housewives to wear. GFAp-
itis. We can talk about it at cocktail parties..."
==========================================================================
*13) Having had the nearly dead dumped on him repeatedly, the very
famous and brilliant (truly) Kenneth B. Liegner of Armonk, New York,
and having had the experience and training to go with the bodies,
decided to send samples of multiply-treated human bodies to the
crooks, to have THEM determine whether or not Lyme infection persists
past treatment and VIOLA!
CDC participates in (Liegner) autopsy and identifies persisting
DNA in samples of patients treated many times for Lyme, which
therefore proves antibiotic treatment does not completely eradicate
the Lyme infection.
SUNY, Tulane, CDC, The Mayo Clinic...
All reported "POSITIVE FOR BORRELIA" either by staining or by DNA
methods.
And then the New York Medical Board tortured Ken what else is new.
Kaiser supplies the New York Medical Board's "experts" from New
York Medical College. It's sorta like the George Bush, Karl Rove, US
Attorneygate, Alberto Gonzales and John Yoo scenario. Stack the deck,
then commit the crime.
==========================================================================
14) Again, in a repeat of Robert Schoen's scare-mongering of the
already mortally scared of having nothing to talk about at cocktail
parties, East Lyme, Connecticut's Vijay Sikand said at the 1998 FDA
LYMErix Vaccine Meeting
"...the specter of asymptomatic infection is something that
troubles me a great deal and troubles a great number of my colleagues
who need to treat Lyme disease. The obvious analogy with syphilis
infection with Treponema pallidum is there to consider. It is well
known that Borrelia burgdorferi indeed after asymptomatic infection
can lurk or secrete itself in certain areas of the body, perhaps the
central nervous system or perhaps the joint spaces, only to reappear
months or maybe years later in the form of late stages of illness
which are harder to diagnosis and treat." ---Vijay Sikand
"OOoohh!
"Scare me!
"Do that again!!!"
<squeal of delight>
["Harder to diagnose and treat?" I thought Lyme was "easily
diagnosed and cured?" Sikand sounds remarkably like myself when I say
"TROJAN HORSE." Or maybe it's the other way around.]
==========================================================================
15) The combined National Institutes say: --
http://intramural.nimh.nih.gov/inip/call4proposals.htm
"8. Infectious diseases of the CNS mediated through immune
mechanisms, including acute and chronic Lyme disease and neuroAIDS;"
Heavens! Who are we to argue with all of the combined National
Institutes?
==========================================================================
16) Early Brain Invasion by Lyme crook, Jorge Benach.
Benach later sent a letter to the editor of the New York Times
stating that Allen Steere was right, that we Lyme victims are
delusional, and that "Allen Steere has the science on his side," when
you can clearly see that we have Jorge Benach's science as well as
Allen Steere's on our side.
==========================================================================
17) Early Brain Invasion by Ray Dattwyler-
Dattwyler is now the author of the new IDSA "guidelines," where
Lyme is a non-disease.
But this is what he told to the FDA in 1994:
Hence, Lyme is not a knee disease, and the Klempner report is
bogus, so there is no data to support the new IDSA guidelines on Lyme
as an imaginary, self-limited disease that is cured by the placebo
effect of antibiotics as Mark Klempner asserted.
This has other indictment value as regards Steere and what he did
in Europe, since clearly we want to diagnose the earliest case of Lyme
to possibly prevent brain invasion. (I know. Steven Malawista and
the Yale Psychiatry Department would not agree with me.)
==========================================================================
18) Pachner_Brains_1990 Antigenic variation in the brain.
This means you can't use the Dressler-Steere antibody method to
determine late Lyme in the brain and neither can you say what Mark
Klempner now says. This is just one more well-established report on
Lyme as a brain disease by a well-acknowledged authority. This report
adds nothing as regards permanence of the infection, since it is not a
treatment study, but it's simply the pursuit of the obvious to anyone
who cares about reality.
==========================================================================
*19) IDSA REVIEWS 1989 IDSA reviews demonstrate that the REAL
expert, Russell Johnson claims that some spirochete cultures could
take months to re-grow intact spirochetes from the spheroplast form
(serum-starvation or survival in harsh conditions form). This negates
the Klempner report.
"Treatment fails in more than half the cases"- Dattwyler, Luft,
Sigal and Steere.
RUSSELL JOHNSON, CULTURING "spheroplasts could take months to
revert to intact spirochetes in BSK media"
NEW "GREAT IMITATOR," PACHNER (We have enough data to work this
up now. We had it over a decade ago. The creeps kept the lid on the
truth and now American scientists are known as "stupid and
incomprehensible" in Europe. The CT Attorney General had to sue the
bastards, they refused to turn over their own self-incriminating data
to him, and the settlement looks very much like they want to avoid
criminal charges. They threw a fit when we laughed at their response
to the settlement with Richard Blumenthal. We laughed some more. Now
they say nothing, except for Edward McSweegan who has become more
virulent against myself, in particular, which is in itself a clue as
to what he doesn't want the world to see. We say "Grow the Eff up and
accept responsibility for what you have done, since there's no better
example of a coward than he who blames the victim and the world is
obviously watching...")
DURAY, CLINICAL PATHOLOGICAL CORRELATES
ABNORMALITIES OF THE NERVOUS SYSTEM, HALPERIN
DATTWYLER and LUFT, IMMUNOLOGICAL ASPECTS
TMT of SYPHILIS, CEFTRIAXONE RECOMMENDED, ENDPOINT UNKNOWN
"Recent evaluations of ceftriaxone for early syphilis therapy are
promising; however, the optimal dose and duration of therapy are
unknown."
CDC's GEORGE SCHMID on LYME and SYPHILIS' SIMILARITIES
Thirty days of IV ceftriaxone was in the first place, an arbitrary
decision by the crooks, themselves,
and that was because they thought it was a brain disease, and the
same for syphilis.
Then, again, came Mark Klempner.
=======================================================================
20) John Dunn at Brookhaven et al, say that Lyme is "the perfect
stealth pathogen" that can "mistaken for MS, Lupus, can cause
excruciating headaches."
Oh.
It's always nice to have the Department of Defense and the
Department of Energy on your side :)))
=======================================================================
*21) Alan Barbour on what happens if you wait long than 7 days to
treat Lyme very aggressively
Remember, now, there is the issue with mice not being the best
human brain example [fill in the blank self-ass-biting comment]:
http://www.ncbi.nlm.nih.gov/ 8913478
Antimicrob Agents Chemother. 1996 Nov;40(11):2632-6
In vivo activities of ceftriaxone and vancomycin against Borrelia
spp. in the mouse brain and other sites.
Kazragis RJ, Dever LL, Jorgensen JH, Barbour AG.
Department of Medicine (Infectious Diseases), University of Texas
Health Science Center at San Antonio 78284, USA.
Borrelia burgdorferi, the agent of Lyme disease, and B. turicatae,
a neurotropic agent of relapsing fever, are susceptible to vancomycin
in vitro, with an MIC of 0.5 microgram/ml. To determine the activity
of vancomycin in vivo, particularly in the brain, we infected adult
immunocompetent BALB/c and immunodeficient CB-17 scid mice with B.
burgdorferi or B. turicatae. The mice were then treated with
vancomycin, ceftriaxone as a positive control, or normal saline as a
negative control. The effectiveness of treatment was assessed by
cultures of blood and brain and other tissues. Ceftriaxone at a dose
of 25 mg/kg of body weight administered every 12 h for 7 to 10 days
eliminated cultivable B. burgdorferi or B. turicatae from all BALB/c
or scid mice in the study. Vancomycin at 30 mg/kg administered every
12 h was effective in eliminating infection from immunodeficient mice
if treatment was started within 3 days of the onset of infection. If
treatment with vancomycin was delayed for 7 days or more, vancomycin
failed to eradicate infection with B. burgdorferi or B. turicatae from
immunodeficient mice. The failure of vancomycin in eradicating
established infections in immunodeficient mice was associated with the
persistence of viable spirochetes in the brain during antibiotic
treatment. PMID: 8913478 [PubMed - indexed for MEDLINE]
See the Chronology of the Lyme crimes for the older references
Identify the disease early and treat it aggressively, but always
remember the Trojan Horse, so avoid psychiatry, because they, in their
hysteria and hissy-fitting response to this website and the proofs
that Lyme is a permanent brain infection, dared to say, "There will be
no more spirochete-like discoveries."
To which we reply, "We think it's a free-for-all, now, and anyone
can make up any diseases they want, as long as you psychiatrists claim
to have the magical ability to diagnose us with anything without the
use of any scientifically valid tests."
I say, "RETROCHONDRIA!!" in your general direction.
I say, "The AMA has FLACCITUDE!"
"Your ideas are Steereborn!!"
We say, "Meet me at the Yale Center for the Study of Erections,
and we can have a discussion about all your uncomplicated variables ."
==========================================================================
22) An independent study on spirochetes in the brain from
dentists and they say:
Molecular and immunological evidence of oral Treponema in the
human brain and their association with Alzheimer's disease.
http://www.ncbi.nlm.nih.gov...11929559 medline link to verify
Riviere GR, Riviere KH, Smith KS.
Department of Pediatric Dentistry, School of Dentistry, Oregon
Health and Sciences University, Portland, OR 97201-3097, USA.
The purpose of this investigation was to use molecular and
immunological techniques to determine whether oral Treponema infected
the human brain. Pieces of frontal lobe cortex from 34 subjects were
analyzed with species-specific PCR and monoclonal antibodies. PCR
detected Treponema in 14/16 Alzheimer's disease (AD) and 4/18 non-AD
donors (P < 0.001), and AD specimens had more Treponema species than
controls (P < 0.001). PCR also detected Treponema in trigeminal
ganglia from three AD and two control donors. Cortex from 15/16 AD
subjects and 6/18 controls contained Treponema pectinovorum and/or
Treponema socranskii species-specific antigens (P < 0.01). T.
pectinovorum and/or T. socranskii antigens were also found in
trigeminal ganglia and pons from four embalmed cadavers, and 2/4
cadavers also had Treponema in the hippocampus. These findings suggest
that oral Treponema may infect the brain via branches of the
trigeminal nerve.
PMID: 11929559 [PubMed - indexed for MEDLINE]
"PCR detected Treponema in 14/16 Alzheimer's disease (AD) and 4/18
non-AD donors."
"Cortex from 15/16 AD subjects and 6/18 controls contained
Treponema pectinovorum and/or Treponema socranskii species-specific
antigens."
We wondered why this information never makes breaking headline
news as regards new developments in Alzheimer's but then we remember
the American Psychiatric Association has become like the Pope in his
treatment of Galileo. Such is heresy against the dogma that "no more
spirochete-like discoveries will be made."
Despite the history and syphilis and the insane asylums and
Ehrlich's Compound 606, the arsenic bullet and so on and so forth...
==========================
23) Mousehausen's is now official CDC admits ceftriaxone fails to
eradicate all spirochetes.
http://aac.asm.org/cgi/content/abstract/AAC.01050-07v1
Persistence of Borrelia burgdorferi Following Antibiotic
Treatment in Mice
Emir Hodzic, Sunlian Feng, Kevin Holden, Kimberly J. Freet,
and Stephen W. Barthold*
Center for Comparative Medicine, Schools of Medicine and
Veterinary Medicine, University of California at Davis, One Shields
Avenue, Davis, CA 95616
The effectiveness of antibiotic treatment was examined in a
mouse model of Lyme borreliosis. Mice were treated with ceftriaxone or
saline for one month, commencing during the early (3 weeks) or chronic
(4 months) stages of infection with Borrelia burgdorferi. Tissues from
mice were tested for infection by culture, polymerase chain reaction
(PCR), xenodiagnosis, and transplantation of allografts at 1 and 3
months after completion of treatment. In addition, tissues were
examined for spirochetes by immunohistochemistry. In contrast to
saline-treated mice, mice treated with antibiotic were consistently
culture-negative, but tissues from some of the mice remained PCR-
positive, and spirochetes could be visualized in collagen-rich
tissues. Furthermore, when some of the antibiotic treated mice were
fed upon by Ixodes scapularis ticks (xenodiagnosis), spirochetes were
acquired by the ticks, based upon PCR, and ticks from those cohorts
transmitted spirochetes to naïve SCID mice, which became PCR-positive,
but culture-negative. Results indicated that following antibiotic
treatment, mice remained infected with non-dividing but infectious
spirochetes, particularly when antibiotic treatment was commenced
during the chronic stage of infection.
Ya gonna argue with the CDC, now?
spirochetes were acquired by the ticks
Culture negative means nothing, as we know. It could take
months in vitro. They should have completed the Mouse Infectivity
Test.
=============================
24)
http://www.ncbi.nlm.nih.gov/pubmed/17045505?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
-
CDC on intracellular nerve and brain borrelia spirochetes
We all wonder how the hell the CDC can talk about this phenomenon
and not come right and say "Lyme is a relapsing fever organism and is
incurable due to their intracellularity and the formation of dormant
cyst or spheroplast forms, which are also inhalable," - since this is
all either their own data, or the NIH's data, or the US Army's data.
================================
25) Willy Burgdorfer discussing the cyst or the spheroplast
form. Combine that with the reality that CDC officers discuss
intracellular spirochetes (Mark Klempner and the one above). While
Willy Burgdorfer is discussing European articles, however - disclaimed
as invalid by the CDC except when Allen Steere does it (Chapter 3) -
recall that Willy Burgdorfer was himself recruited by the NIH Rocky
Mountains Bioweapons Lab (which had a moat dug around it hmmm
strangely like a mini island, like a mini Plum Island) from
Switzerland, and the NIH also recruited the German scientist Roland
Martin to head up the NINDS-Multiple Sclerosis group.
So, everyone can discount CDC's discount of foreign research since
obviously no matter what they say, it's a lie.
==================================================
SAY THE IDSA GUIDELINES (GARY WORMSER, et al, or the Original
ALDF.com "entrepreneurial trio" gang of:
"The entrepreneurial trio are Durland Fish, Ph.D.,
former director of the College's Lyme Disease Center and now a
research scientist at Yale; Gary P. Wormser, M.D., still professor of
medicine and pharmacology and chief of the Division of Infectious
Diseases at the College; and John J. Connolly, Ed.D., former College
president and current chairman of the board of the American Lyme
Disease Foundation, Inc., which had its genesis on the Valhalla
campus in 1990."
http://www.journals.uchicago.edu/doi/full/10.1086/508667 ◄ "The
2006 IDSA Guidelines"
"The notion that symptomatic, chronic B. burgdorferi infection
can exist despite recommended
treatment courses of antibiotics (tables 2 and 3) in the
absence of objective clinical signs of
disease, is highly implausible as evidenced by (1) the lack of
antibiotic resistance in this genus
[39, 40, 310], (2) the lack of correlation of persistent
symptoms with laboratory evidence of
inflammation or with the eventual development of objective
physical signs [223, 257, 288, 289],
and (3) the lack of precedent for such a phenomenon in other
spirochetal infections [315-317].
[Lyme is a "STEALTH DISABLER" and as shown in the Yale
Congenital Lyme Autopsy report, there was "NO INFLAMMATION." SEE THE
BIOMARKERS and the MARK KLEMPNER CHAPTER; NOT CAPTURING THEIR OWN
IDENTIFIED BIOMARKERS of disease and instead, deploying the invalid
mumbo-jumbos (psychiatry) is a research fraud crime.]
"Additional compelling evidence against the hypothesis that
persistent symptoms are the result of
persistent infection is the fact that the concentrations of
antibodies against B. burgdorferi in
many of these patients diminish to undetectable levels [257,
286, 288, 318]. The panel is unaware
of any chronic infection in which antibody titers diminish
despite persistence of the causative
organism. [VERY DAMNING statement. This phenomenon is related
to the "stealth disabler" mechanisms of fungal or mycoplasmal or
mycobacterial antigens- no antibodies are made against the infection
due to TLR2 tolerization and the downregulation of HLA or antigen-
presenting molecules Wormser is aware of the immune suppression
aspects of OspA vaccination, since he reported about it:
Gary Wormser reporting the blunting of the immune response
in vaccinated animals:
http://www.ncbi.nlm.nih.gov/pubmed/10865170?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
"OspA interferes with the response of lymphocytes to
proliferative stimuli including a blocking of cell cycle phase
progression."
"In syphilis, patients who are regarded as having treatment
failure typically have persistent or rising titers of antibodies
[319]. [THE IMMUNE SUPPRESSING PlumIsland PAM3CYS LIPOPEPTIDE OSPA IS
NOT FOUND IN TREPONEMA PALLIDUM]
"Finally, Lyme disease lacks characteristics of other
infections that justify longer treatment courses, such as infections
in immunodeficient hosts, [YOU ARE REALLY GONNA BE SHOCKED when you
see the Plum Island Mycoplasmal-immune suppressing data, the
activation of latent viruses data (auto-kill turned off) the HIV
Pam3Cys immune depression data, and the Fungal Vaccines data]
infections in which a pathogen is inhibited but not killed by
antimicrobial therapy or in which available antimicrobials are
minimally active in vitro [JOHNSON CULTURING FROM SPHEROPLAST COULD
TAKE MONTHS], infections caused by an intracellular pathogen
[KLEMPNER- "cef fails"], infections involving a biofilm, infections on
a heart valve, or infections involving a clinical site in which there
is ischemia, a foreign body, a sequestrum***, or frank pus [170]. The
“cystic” forms of B. burgdorferi that have been seen under certain
growth conditions in vitro have not been shown to have any clinical
significance [320]. [INTRACELLULAR CYSTS are the KEY TO LATENCY, well-
known historically, and this is an application of the NEGATIVE DATA
RULE, which is another research fraud crime indictment point; THE
MOUSE INFECTIVITY TEST HAS NOT BEEN PERFORMED ON TREATED MICE OR
MONKEYS]
CDC and NIH Rocky Mountain antibody-gold sphere method
as applied to borreliosis:
The Method Developed:
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=261539&blobtype=pdf
*** Applied to Borreliosis by NIH Rocky Mountain Lab:
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=269963&blobtype=pdf
The Dorward/Garon Gold Test Apparently detects plenty
of shed antigen. And it looks pretty sequestery to me, not to mention
we could never determine sequestery sites in a human unless we had a
lot of brains to biopsy, although the dentists did a pretty good job
detecting oral treponemes sequestering in the brains of Alzheimer's
patients- See Item 23, below.
1975 at an international spirochetal diseases conference
for which Willy Burgdorfer was present; "The ability of the borrelia,
especially tick-borne strains to persist in the brain and in the eye
after treatment with arsenic or with penicillin or even after apparent
cure is well known (1). The persistence of treponemes after treatment
of syphilis is a major area which currently requires additional study
(3,5,10,11)." -Jay Sanford, US Military Hospital, Bethesda, MD
As you can see, Gary Wormser, ad IDSA et al, are trying to
deny everything that Lyme actually is. Lyme is stealth (no antibodies
late in the disease), latent, intracellular, is resistant to
antibiotics (goes into a self-protective spheroplast form upon
exposure to antibiotics which is not an "end stage" as the crooks
claim), it goes into a "dormant" or serum-starved or spheroplast mode
(known to the crooks themselves as a "Trojan Horse"), Lyme belongs to
the class of diseases where there is typically no inflammation. It
does not belong to NIAID or Anthony Fauci's division, but the
parasitic diseases division - but it's not going to belong to either
the CDC or the NIH at all after not too long, because when they're
done being investigated we will find that that NIH and the CDC are the
same as the NEJM "peer-reviewers" - not a one of them isn't interest
conflicted. In fact, we will find out what is the exact relationship
between the CDC and Kaiser or else the NAFTA-eers of Canada and Mexico
will discover it and prosecute it.
At this time I recommend that Russia and China infiltrate
Canadian and Mexican business structures such that when the NAFTA
NationRape of the North American Continent takes place, Russia can
return the favor for the Israeli Oligarchic NationRape Escapade under
Yeltsin.
More of these clear rebuttals below and in the
RICOCHRON.htm page.
Remember, the IDSA keywords: "INFLAMMATION" and "OBJECTIVE
SIGNS" (meaning they are still referring to "Lyme Disease" as the
Dearborn definition of "autoimmune bad knee" as seen in the RICO
graphics), because that later comes in in Congenital Lyme ("lack of
inflammation") and the Biomarkers chapter as regards the description
of the immune suppression outcomes of Lyme, which is the key to all of
their crimes, especially as regards this fungal vaccine, LYMErix or
ImmuLyme, or rOspA and the activation of latent viruses of all kinds.
The crooks' own treatment failure or persistence articles
are below.
The IDSA statement about the cysts or the spheroplasts is
yet another criminal matter, since they all referenced Dave Nelson's
"reversion to intact spirochete form from spheroplast within one
minute of the addition of rabbit blood" report, Russell Johnson said
it could take months in culture for the cyst form to regenerate in
media, and the Mouse Infectivity Test has never been tried as a
treatment efficacy trial, ever, to my knowledge in lab animals. They
cannot make the claim that the cyst form hasn't any clinical
significance, since here we have again the Crooks' Negative Data Rule.
At the present time, there are a whole slew of Russian
scientists now studying these intracellular serum-starvation
("Stringent Response") forms at New York Medical College.
http://iai.asm.org/cgi/reprint/70/6/3061
It's pretty hard to find a cohort nowadays of non-HIV
infected syphilis patients. From the 1989 IDSA reviews chapter on
syphilis, it does not sound at all like syphilis is under control or
even given much concern
The serology of syphilis and borreliosis can hardly be
compared anyway due to the fact that Borrelia infect all kinds of
mammals and undergo great antigenic variation. These IDSA criminals
deny the validity of the Borrelia-specific flagellin assays, when
they're the only valid assays.
Anything Wormser says at all needs to be challenged. It's
quite self-evident that nothing about the seriousness of this disease
will Wormser tolerate as a fact to stand out or rise to the surface or
be memorable. Clearly that attack pattern worked in the past as
regards the Tuskegee Bad Blood experiment and it worked for a while as
regards the abuse of Gulf War Illness Veterans, and it works fine as
long at the Lyme Disease Association's Pat Smith insists her drones do
nothing other than worship Pat Smith and pretend to be Stepford Wives
- as if it were admirable to be a brainless-but-pretty robot. But
here is an era where all of these types of abusive medical criminals'
former barriers have come down.
We all know psychiatry is not a medical practice and that
the entire genre is in an embarrassing shambles of BigPharma pay-offs
and incredibly stupid, self-indicting statements every time they're in
the news. They undid themselves because they went exponentially
overboard with their relationships to BigPharma. The Lyme criminals
can no longer deploy psychiatry as they have in the past. Roy Meadows
was himself a fulcrum for change due to the obvious ridiculousness of
the Munchausen's accusations. Sooner or later it would have happened
that someone mentioned the word science in the context of health, when
talking about children and death.
The survivors of the Munchausen's Terror can take comfort
in the fact that God allowed this horror to occur, like He allowed the
Child Protective Services to happen. God intends to send at least 2/3
of all the humans to hell. If you're a survivor of these Terrors,
you've been chosen to send dozens of people to hell for your
suffering. In your suffering, you are suffering with Christ, and He
is pleased with such people the most.
When Jesus said, "the gates of heaven are narrow," and
that few would make it, He would not be lying, would He?
Anyone who has dealt with the Child Protective Services
has no doubt that it is their personal will to torture parents and
children and that they take great pleasure and derive great
satisfaction in destroying people and causing great suffering You can
see it in their queer, sneering, half-cocked smiles. When you know
the CPS, there is no question in your mind that these entities are
demonic. The vast majority of them are either possessed or are far
along the way towards possession. (The only time a possessed person
acts out is when they are attempting to reject the possession. The
rest are asymptomatic, like the CPS and psychiatrists.)
And given the magnitude of this epidemic of Lyme there
had to be an instance where a tick would bite a real scientist.
Perhaps it only happened once, but it happened. A real scientist is
someone who shouts "BULLSHIT!!," in addition to being highly sensitive
to bullshit's occurrence- which would only happen if said scientist is
also a female. We have no other data on that because none exists, or
else, by definition we would hear about it.
COMPREHENSIVE ARTICLE ON SYPHILIS:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16418521
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1048219&blobtype=pdf
http://www.ourladyswarriors.org/prayer/michael.htm
Saint Michael the Archangel,
defend us in battle.
Be our protection against the wickedness and snares of the devil.
May God rebuke him, we humbly pray;
and do Thou, O Prince of the Heavenly Host -
by the Divine Power of God -
cast into hell, satan and all the evil spirits,
who roam throughout the world seeking the ruin of souls.
Amen.
Spin...@yahoogroups.com, kshe...@calea.org, fit...@gmail.com,
patrick.f...@usdoj.gov, model...@sbcglobal.net,
jdr...@nejm.org, let...@courant.com, Jgerb...@cdc.gov,
michae...@po.state.ct.us, con...@po.state.ct.us, executive-
edi...@nytimes.com, managin...@nytimes.com, news-
ti...@nytimes.com, the-...@nytimes.com, biz...@nytimes.com,
for...@nytimes.com, nati...@nytimes.com, dv...@cdc.gov,
brigidc...@optonline.net, tr...@hotmail.com, illino...@aol.com,
jle...@courant.com, tinaj...@yahoo.com, jhorn...@fff.org,
thomas...@usdoj.gov, thoma...@po.state.ct.us,
kur...@washpost.com, georg...@washpost.com, p...@allegorypress.com,
commissi...@po.state.ct.us, brans...@comcast.net,
vts...@comcast.net, o...@po.state.ct.us, freet...@charter.net,
scott....@po.state.ct.us, govern...@po.state.ct.us,
attorney...@po.state.ct.us, randall...@usdoj.gov,
Robert....@yale.edu, edi...@greenwich-post.com
Cc: fra...@ucia.gov, dr-ahma...@president.ir,
eugener...@washpost.com, afa...@niaid.nih.gov,
bmi...@newstimes.com, tr...@hotmail.com, rast...@aol.com,
billc...@gmail.com, amcg...@rms-law.com, rjmu...@aol.com,
paulcrai...@yahoo.com, sidney_b...@yahoo.com,
criminal...@usdoj.gov, karla.d...@usdoj.gov,
christophe...@usdoj.gov, richar...@yale.edu,
harol...@yale.edu, james.p...@yale.edu, inq...@aldf.com,
ly...@idsociety.org
Subject: JAMA tells a funny story
Date: Feb 10, 2009 6:21 PM
http://jama.ama-assn.org/cgi/content/full/301/6/665
"The case exemplifies the politicization of health policy, with
elected officials advocating for health policies against the weight of
scientific evidence."
=================================
Oh.
Ya mean there's someone besides IDSA, the US Military,
and the CDC who has proven scientifically that spirochetes
are not permanent infections that go into latency... like
chicken pox and shingles?
http://www.actionlyme.org/BRAIN_PERMANENT.htm
http://www.actionlyme.org/RICOCHRON.htm
*1) In 1975 there was apparently an international conference on
spirochetal diseases. The following year the conference was
summarized in book form, by Russell Johnson and was entitled, The
Biology of Parasitic Spirochetes.
Dr. Jay Sanford of the "Uniformed Services Military Hospital" in
Bethesda, Maryland, reported:
"The ability of the borrelia, especially tick-borne
strains to persist in the brain and in the eye after treatment with
arsenic or with penicillin or even after apparent cure is well known
(1). The persistence of treponemes after treatment of syphilis is a
major area which currently requires additional study (3,5,10,11)." -
Jay Sanford, US Military Hospital, Bethesda, MD
Russell Johnson later published for the 1989 IDSA Reviews, special
supplement on Lyme and spirochetal diseases that: "Although
spirochetes can often be detected in culture media after 3 weeks of
culture, some isolates may not be visible for several months."
IDSA says we need to culture these suckers for several months.
Did Mark Klempner do that in his bogus long term treatment "study?"
NO.
=================================================================
2) http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=373079&blobtype=pdf
By CDC Officer Alan Barbour, in 1986, The Biology of Borrelia
Species:
"The propensity for borrelia to go to the brain of infected
mammals suggests that the relationship between these spirochetes and
neural tissues is not trivial. Further study of this attraction and
the interaction that follows may reveal the basis for the significant
nerve and brain involvement in Lyme borreliosis"--
This is self-explanatory. We have previously seen that rodent
brains so reliably were a home for spirochetes that they were actually
the culture media. We also acknowledge that ceftriaxone for brain
diseases was a treatment IDSA themselves used and offered and still
use, so Lyme must not be a self-limiting knee disease as Allen Steere
and Yale's Steven Malawista claim.
And here we have in the same CDC officer's 1986 report that there
are, gasp, "gemma:"
[You want to GO HERE for other older references published
before the Great Whore of Medicine, Allen Steere emerged onto the
scene]
=================================================================
3) Russell Johnson's patent for the very first Lyme vaccine
US PATENT 4,721,617
"The chronic forms of the disease such as arthritis (joint
involvement), acrodermatitis chronica atrophicans (skin involvement),
and Bannwart's syndrome (neurological involvement) may last for months
to years and are associated with the persistence of the spirochete. A
case of maternal-fetal transmission of B. burgdorferi resulting in
neonatal death has been reported. Domestic animals such as the dog
also develop arthritis and lameness to this tick-borne infection. For
every symptomatic infection, there is at least one asymptomatic
infection. Lyme disease is presently the most commonly reported tick-
borne disease in the United States." --
The patent also says:
"The infection may be treated at any time with antibiotics
such as penicillin, erythromycin, tetracycline, and ceftriaxone. Once
infection has occurred, however, the drugs may not purge the host of
the spirochete but may only act to control the chronic forms of the
disease. Complications such as arthritis and fatigue may continue for
several years after diagnosis and treatment."
=============================================================
4) At the time of the writing of this book, CDC officer Alan
Barbour has on his website, the following statement:
"We are taking a multi-discipline approach, including methods
of genetics, cell biology, and immunology, to study in depth two
spirochetal diseases: Lyme disease and relapsing fever. These tick-
borne infections are notable for multiphasic antigenic variation
through DNA recombinations in the case of relapsing fever, the
occurrence of chronic arthritis in the case of Lyme disease, and
invasion of and persistence in the brain in the case of both
diseases. ---Alan Barbour
============================================================
*5) In 1994 Alan Steere and other published a report entitled:
http://www.annals.org/cgi/content/full/121/8/560
The Long-Term Clinical Outcomes of Lyme Disease: A Population-
based Retrospective Cohort Study
right arrow Nancy A. Shadick; Charlotte B. Phillips; Eric L.
Logigian; Allen C. Steere; Richard F. Kaplan; Victor P. Berardi; Paul
H. Duray; Martin G. Larson; Elizabeth A. Wright; Katherine S.
Ginsburg*; Jeffrey N. Katz; and Matthew H. Liang
15 October 1994 | Volume 121 Issue 8 | Pages 560-567
In that report:
"Patient 12 had had high fever, meningeal symptoms, and
subsequent arthritis in 1982. She was noted to have a positive
serologic test result for Lyme disease 4 years later and was treated
with 2 weeks of parenteral penicillin. She later developed a
progressive speech disorder, bradykinesia, and abnormal ocular motor
function. Magnetic resonance imaging of the brain showed scattered
white matter lesions in the hemispheres and pons, and she was
diagnosed with supranuclear palsy. Lumbar puncture showed no selective
concentration of antibody in the spinal fluid. Nevertheless, she was
re-treated with 2 weeks of parenteral ceftriaxone in 1989 that had no
effect on her neurologic symptoms. During the time of observation,
this patient died. At autopsy, lymphoid mononuclear cells were
observed surrounding the intracerebral vessels in one section. Using
Dieterle silver stain, a spirochete was present in the cortex and
another was exterior to a leptomeningeal vessel."
One of Steere's multiply-treated patients died anyway with
spirochetes in her brain. How amazing that that suddenly doesn't
happen any more, despite no new breakthroughs in antibiotic treatments
or their delivery.
The Primer's Shell Game is where these Lyme crooks use the
wrong DNA (or RNA) primers (they use the variable Osp primers instead
of the non-variable chromosomally encoded) to test Lyme victims.
These same crooks use the correct DNA primers when they want to find
Lyme or borrelia in ticks (to patent). It's a shell game. They all
know that all that they can use for treatment outcomes is non-variable
DNA or RNA.
Mark Klempner never reported his primers in his Chronic
Lyme "study," and he would not tell me, either, in an email
correspondence I had with him. Therefore, the Lyme crooks have never
validly reported on the presence of borrelia in humans, with the
exception of Gary Wormser's study of EMs in which he found 2/9
patients who had EM, who had been treated with antibiotics still had
spirochetes in their tissues. This data can be found on the HOW RICO
WILL BE CHARGED PAGE
- - -
Clin Microbiol Infect. 2008 Jul;14(7):653-8.
Comparison of PCR methods and culture for the detection of
Borrelia spp. in patients with erythema migrans.
http://www.ncbi.nlm.nih.gov/pubmed/18558937?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
Cerar T, Ruzić-Sabljić E, Glinsek U, Zore A, Strle F.
Institute of Microbiology and Immunology, Faculty of
Medicin, University of Ljubljana, Slovenia. tjasa...@mf.uni-lj.si
The sensitivities of two PCR assays and culture were
compared for the detection of Borrelia spp. in skin specimens of 150
patients with typical erythema migrans. In addition, the accuracy of
the methods for the identification of Borrelia spp. was compared by
analysing culture isolates and material obtained directly from skin
biopsy specimens. Borrelia burgdorferi sensu lato was isolated from 73
(49%) of 150 skin biopsy specimens. Using a nested PCR targeting the
rrf-rrl region and a PCR targeting the flagellin gene, 107 (71%) and
36 (24%) specimens, respectively, were positive. With both PCRs,
positive results were more frequent with culture-positive samples
(67/73 (92%) and 24/73 (33%) for the nested and flagellin PCRs,
respectively) than with culture-negative samples (40/77 (52%) and
12/77 (16%) for nested and flagellin PCR, respectively). Pulsed-field
gel electrophoresis after MluI restriction identified 69/73 (95%)
isolates, of which 58/69 (84%) were Borrelia afzelii and 11/69 (16%)
were Borrelia garinii. After MseI restriction of PCR products
amplified from the intergenic rrf-rrl region, B. afzelii was
identified in 73/107 (68%) samples, B. garinii in 22/107 (21%)
samples, and both species in 11/107 (10%) samples. The corresponding
results for culture-positive specimens were 41/69 (59%), 14/69 (20%),
and 7/69 (10%). Comparison of the results for specimens positive
according to both approaches revealed complete uniformity in 80% of
the cases. Overall, nested PCR was the most sensitive method for the
demonstration of Borrelia spp. in erythema migrans skin lesions,
followed by culture and PCR targeting the flagellin gene. The
congruence of identification results obtained by analyzing culture
isolates and material obtained directly from skin biopsies was
relatively high but incomplete.
The Borrelia Flagellin Master Prober: Picken, 1992:
http://jcm.asm.org/cgi/reprint/30/1/99?view=long&pmid=1734073
Burgdorferi is most similar to hermsii
Mark Klempner, in his fake long term retreatment study, did
not reveal which DNA primers he used to discover no-lyme in the CSF of
previously terated Lyme victims, even when asked directly. The NEJM
had no problem with Klempner not reporting his Methods and Materials
in the Methods and Materials section of his report.
http://content.nejm.org/cgi/reprint/345/2/85.pdf
Klempner states in his report that people who were positive
were excluded from the study because it would be unethical not to
treat patients who were DNA positive for Borrelia, and so they were
excluded from the start. We know of at least one patient who joined
Klempner's study because she/he was Borrelia burgdorferi DNA-positive.
For Klempner to claim publicly that there were no Bb DNA
positive patients at all, is research fraud.
Recall from the Russell Johnson Culturing article published in
the 1989 IDSA Reviews special supplement on Lyme and spirochetal
diseases, it could take months to regrow intact spirochetes in BSK
media from the cystic form:
===============================================================
*6, 7) In 1994 and in 1996, Steere and Nocton published a reports
of treatment failure and brain invasion using RNA and DNA methods and
they found treatment failed in a third of the patients with their OspA
primer sets. In the first report, in 1994, published in the New
England Journal of Medicine, that they used 4 primer sets. Three were
for the OspA gene (which we know undergoes antigenic variation and
therefore these are the wrong probes). The fourth set was for 16S RNA
intragenic spacer (remember now, for Borrelia burgdorferi, ignoring
all the other possibilities). These were rather valuable reports,
overall, since they prove that Allen Steere and the ALDF cabal is
saying something much different today about the what the disease
actually is (brain infection) and about treatment outcomes.
http://content.nejm.org/cgi/content/full/330/4/229
Detection of Borrelia burgdorferi DNA by polymerase chain reaction
in cerebrospinal
fluid in Lyme neuroborreliosis.
"of 73 patients with Lyme arthritis who were untreated or
treated with short courses of oral antibiotics before testing, 70 (96
percent) had positive PCR results. In contrast, of 19 patients who
received either parenteral antibiotics or long courses of oral
antibiotics, only 7 (37 percent) had positive test results after
treatment (P<0.001). In the 29 patients for whom serial samples were
available, all pretreatment samples were positive."
Self-explanatory.
About a third of the patients still had spirochetes in their knees
after antibiotic treatment.
- - - -
The following is not a treatment outcomes assessment, but merely
demonstrates that Allen Steere acknowledges the brain disease called
"chronic neuroborreliosis" and that he previously had proven with the
synovial fluid DNA post-treatment analysis, that treatment failed in a
third of the cases. As I do not have the full text of this report,
and the probes were not reported, I can't comment on whether or not
they were the correct ones. As the correct ones by this time had been
used by Gary Wormser and Robert Schoen when assessing tick bite
treatment outcomes and whether or not the spirochete missing the OspA-
B plasmid belonged to this new New England deer tick relapsing fever
group, respectively, we can guess that Allen Steere maybe knew which
primer probes to use: 16S and 23S RNA, but better from more from the
genera:
http://www.ncbi.nlm.nih.gov/pubmed/8769624
Detection of Borrelia burgdorferi DNA by polymerase chain
reaction in cerebrospinal fluid in Lyme neuroborreliosis.
: J Infect Dis. 1996 Sep;174(3):623-7.
Nocton JJ, Bloom BJ, Rutledge BJ, Persing DH, Logigian EL, Schmid
CH, Steere AC.
Division of Rheumatology/Immunology, New England Medical Center,
Boston, Massachusetts02111, USA.
A polymerase chain reaction (PCR) assay that detects Borrelia
burgdorferi DNA in cerebrospinal fluid (CSF) was evaluated as a
diagnostic test for acute or chronic Lyme neuroborreliosis. In one
laboratory, 102 samples were tested blindly, and 40 samples were
retested in a second laboratory. In the first laboratory, B.
burgdorferi DNA was detected in CSF samples in 6 (38%) of 16 patients
with acute neuroborreliosis, 11 (25%) of 44 with chronic
neuroborreliosis, and none of 42 samples from patients with other
illnesses. There was a significant correlation between PCR results and
the duration of previous intravenous antibiotic therapy. The overall
frequency of positive results was similar in the second laboratory,
but concordance between the laboratories and among primer-probe sets
was limited because many samples were positive with only one primer-
probe set. Thus, PCR testing can sometimes detect B. burgdorferi DNA
in CSF in patients with acute or chronic neuroborreliosis, but with
current methods, the sensitivity of the test is limited.
PMID: 8769624 [PubMed - indexed for MEDLINE]
Perhaps the best way to prove antibiotic efficacy is with monkeys
treated with ceftriaxone and then subject to the Mouse (monkey)
Infectivity Test.
=======================================================================
*8, 9)
As reported in the previous chapter, and in the introduction of
this one, Mark Klempner says the IV drug ceftriaxone, which is used
for meningitis (and not knee-only diseases), does not kill all the
spirochetes (click here for full text journal article)
"Fibroblasts protected B. burgdorferi for at least 14 days of
exposure to ceftriaxone. Mouse keratinocytes, HEp-2 cells, and Vero
cells but not Caco-2 cells showed the same protective effect. Thus,
several eukaryotic cell types provide the Lyme disease spirochete with
a protective environment contributing to its long-term survival." HERE
on Medline (same report as above)
Mark Klempner here describes a special nerve and brain
degrading enzyme, Matrix-metalloproteinase 130 that he found in
chronic Lyme patients. Be sure to read why he performed this study.
====================================================================
10) In 1999, Mark Klempner reported with Denise Huber at Tufts,
"Autoimmunity; Is is Me or Thee?"
http://www.nature.com/nm/journal/v5/n12/abs/nm1299_1346.html;jsessionid=47122A0C58C911613E8BDE31ED7C9609
Same report: Klempner reported that OspA or LYMErix could cause
brain disease as if that needs an explainer.
"T cells that react to OspA, OspC and p 22 epitopes also
recognize myelin basic protein, SST-R1m and IL-1R, respectively,
possibly leading to encephalopathy and radiculopathy..."
We're not too impressed with the T cell data to support that
hypothesis, but we are impressed with Mark Klempner's non-reporting
the possible association between OspA vaccination and brain damage,
since in 1999, LYMErix had come onto the market. We're also impressed
with the fact that in 2003 Mark Klempner said there was no such thing
as cognitive impairment associated with Lyme infection. We claim that
myelin has something to do with brains and nerves, and that the spinal
fluid was from whence Mark discovered the very special MMP-130.
NINDS' Roland Martin did not prove T cell autoimmunity, and so he
went home to Germany. Martin failed to prove that the Multiple
Sclerosis version of "Lyme Disease" is caused by T cell autoimmunity,
just as Allen Steere failed to find T cell autoimmunity was the cause
of the knee kind of Lyme. If Lyme-Knee and Lyme-Brain are not really
T cell autoimmunity diseases, then what are they ya think?
Read more about that on this page: 080515.htm
See Mark Klempner's nice flow chart (more detailed version,
HERE):
=======================================================================
*11) Yale Pathology and the Congenital Brain Infection of Newborn
Resulting in Death "The death of the newborn was probably due to
respiratory failure as a consequence of perinatal brain damage."
The child and mother were seronegative, they were treated, and
there was remarkably "no inflammation." Yale's Eugene Shapiro claimed
in PBS' Life on Earth Series that the only way you can have a disease
is if you have inflammation.
The baby died of congenital Lyme brain damage, anyway. This is
not the only such report, and they report on several babies who died
from congenital Lyme.
MORE HERE
==========================================================================
12) When trying to strike fear into the hearts of the New England
Munchausers, hypochondriacs, trophy-wives who co-suffer Viagra-deficit
syndrome, Fibrofemzalgiacs, "what I call Lyme Paranoia, "
antibiomaniacs, members of the "Lyme internet cult," and other
delusional newsgroup posters, Yale's Robert Schoen said about the
LYMErix vaccine:
http://www.annals.org/cgi/reprint/132/8/661.pdf
In late-stage disease [a disease now called Munchausen's by proxy,
etc], the central nervous system [which we know to be a complicating
variable and should be thrown out] may be involved. A new diagnostic
test [not ever to be used, since it is a scientifically valid marker
of real illness and we Lyme crooks never go there, preferring the
services of the professional, perpetual pee-pee whacking Voo-Dooists
of medicine, psychiatry] measuring glial fibrillary acidic protein in
the cerebrospinal fluid may prove to be a useful tool in measuring
such involvement.
"Oh," we say.
"My, my. A new disease for us bored housewives to wear. GFAp-
itis. We can talk about it at cocktail parties..."
==========================================================================
*13) Having had the nearly dead dumped on him repeatedly, the very
famous and brilliant (truly) Kenneth B. Liegner of Armonk, New York,
and having had the experience and training to go with the bodies,
decided to send samples of multiply-treated human bodies to the
crooks, to have THEM determine whether or not Lyme infection persists
past treatment and VIOLA!
CDC participates in (Liegner) autopsy and identifies persisting
DNA in samples of patients treated many times for Lyme, which
therefore proves antibiotic treatment does not completely eradicate
the Lyme infection.
SUNY, Tulane, CDC, The Mayo Clinic...
All reported "POSITIVE FOR BORRELIA" either by staining or by DNA
methods.
And then the New York Medical Board tortured Ken what else is new.
Kaiser supplies the New York Medical Board's "experts" from New
York Medical College. It's sorta like the George Bush, Karl Rove, US
Attorneygate, Alberto Gonzales and John Yoo scenario. Stack the deck,
then commit the crime.
==========================================================================
14) Again, in a repeat of Robert Schoen's scare-mongering of the
already mortally scared of having nothing to talk about at cocktail
parties, East Lyme, Connecticut's Vijay Sikand said at the 1998 FDA
LYMErix Vaccine Meeting
"...the specter of asymptomatic infection is something that
troubles me a great deal and troubles a great number of my colleagues
who need to treat Lyme disease. The obvious analogy with syphilis
infection with Treponema pallidum is there to consider. It is well
known that Borrelia burgdorferi indeed after asymptomatic infection
can lurk or secrete itself in certain areas of the body, perhaps the
central nervous system or perhaps the joint spaces, only to reappear
months or maybe years later in the form of late stages of illness
which are harder to diagnosis and treat." ---Vijay Sikand
"OOoohh!
"Scare me!
"Do that again!!!"
<squeal of delight>
["Harder to diagnose and treat?" I thought Lyme was "easily
diagnosed and cured?" Sikand sounds remarkably like myself when I say
"TROJAN HORSE." Or maybe it's the other way around.]
==========================================================================
15) The combined National Institutes say: --
http://intramural.nimh.nih.gov/inip/call4proposals.htm
"8. Infectious diseases of the CNS mediated through immune
mechanisms, including acute and chronic Lyme disease and neuroAIDS;"
Heavens! Who are we to argue with all of the combined National
Institutes?
==========================================================================
16) Early Brain Invasion by Lyme crook, Jorge Benach.
Benach later sent a letter to the editor of the New York Times
stating that Allen Steere was right, that we Lyme victims are
delusional, and that "Allen Steere has the science on his side," when
you can clearly see that we have Jorge Benach's science as well as
Allen Steere's on our side.
==========================================================================
17) Early Brain Invasion by Ray Dattwyler-
Dattwyler is now the author of the new IDSA "guidelines," where
Lyme is a non-disease.
But this is what he told to the FDA in 1994:
Hence, Lyme is not a knee disease, and the Klempner report is
bogus, so there is no data to support the new IDSA guidelines on Lyme
as an imaginary, self-limited disease that is cured by the placebo
effect of antibiotics as Mark Klempner asserted.
This has other indictment value as regards Steere and what he did
in Europe, since clearly we want to diagnose the earliest case of Lyme
to possibly prevent brain invasion. (I know. Steven Malawista and
the Yale Psychiatry Department would not agree with me.)
==========================================================================
18) Pachner_Brains_1990 Antigenic variation in the brain.
This means you can't use the Dressler-Steere antibody method to
determine late Lyme in the brain and neither can you say what Mark
Klempner now says. This is just one more well-established report on
Lyme as a brain disease by a well-acknowledged authority. This report
adds nothing as regards permanence of the infection, since it is not a
treatment study, but it's simply the pursuit of the obvious to anyone
who cares about reality.
==========================================================================
*19) IDSA REVIEWS 1989 IDSA reviews demonstrate that the REAL
expert, Russell Johnson claims that some spirochete cultures could
take months to re-grow intact spirochetes from the spheroplast form
(serum-starvation or survival in harsh conditions form). This negates
the Klempner report.
"Treatment fails in more than half the cases"- Dattwyler, Luft,
Sigal and Steere.
RUSSELL JOHNSON, CULTURING "spheroplasts could take months to
revert to intact spirochetes in BSK media"
NEW "GREAT IMITATOR," PACHNER (We have enough data to work this
up now. We had it over a decade ago. The creeps kept the lid on the
truth and now American scientists are known as "stupid and
incomprehensible" in Europe. The CT Attorney General had to sue the
bastards, they refused to turn over their own self-incriminating data
to him, and the settlement looks very much like they want to avoid
criminal charges. They threw a fit when we laughed at their response
to the settlement with Richard Blumenthal. We laughed some more. Now
they say nothing, except for Edward McSweegan who has become more
virulent against myself, in particular, which is in itself a clue as
to what he doesn't want the world to see. We say "Grow the Eff up and
accept responsibility for what you have done, since there's no better
example of a coward than he who blames the victim and the world is
obviously watching...")
DURAY, CLINICAL PATHOLOGICAL CORRELATES
ABNORMALITIES OF THE NERVOUS SYSTEM, HALPERIN
DATTWYLER and LUFT, IMMUNOLOGICAL ASPECTS
TMT of SYPHILIS, CEFTRIAXONE RECOMMENDED, ENDPOINT UNKNOWN
"Recent evaluations of ceftriaxone for early syphilis therapy are
promising; however, the optimal dose and duration of therapy are
unknown."
CDC's GEORGE SCHMID on LYME and SYPHILIS' SIMILARITIES
Thirty days of IV ceftriaxone was in the first place, an arbitrary
decision by the crooks, themselves,
and that was because they thought it was a brain disease, and the
same for syphilis.
Then, again, came Mark Klempner.
=======================================================================
20) John Dunn at Brookhaven et al, say that Lyme is "the perfect
stealth pathogen" that can "mistaken for MS, Lupus, can cause
excruciating headaches."
Oh.
It's always nice to have the Department of Defense and the
Department of Energy on your side :)))
=======================================================================
*21) Alan Barbour on what happens if you wait long than 7 days to
treat Lyme very aggressively
Remember, now, there is the issue with mice not being the best
human brain example [fill in the blank self-ass-biting comment]:
http://www.ncbi.nlm.nih.gov/ 8913478
Antimicrob Agents Chemother. 1996 Nov;40(11):2632-6
In vivo activities of ceftriaxone and vancomycin against Borrelia
spp. in the mouse brain and other sites.
Kazragis RJ, Dever LL, Jorgensen JH, Barbour AG.
Department of Medicine (Infectious Diseases), University of Texas
Health Science Center at San Antonio 78284, USA.
Borrelia burgdorferi, the agent of Lyme disease, and B. turicatae,
a neurotropic agent of relapsing fever, are susceptible to vancomycin
in vitro, with an MIC of 0.5 microgram/ml. To determine the activity
of vancomycin in vivo, particularly in the brain, we infected adult
immunocompetent BALB/c and immunodeficient CB-17 scid mice with B.
burgdorferi or B. turicatae. The mice were then treated with
vancomycin, ceftriaxone as a positive control, or normal saline as a
negative control. The effectiveness of treatment was assessed by
cultures of blood and brain and other tissues. Ceftriaxone at a dose
of 25 mg/kg of body weight administered every 12 h for 7 to 10 days
eliminated cultivable B. burgdorferi or B. turicatae from all BALB/c
or scid mice in the study. Vancomycin at 30 mg/kg administered every
12 h was effective in eliminating infection from immunodeficient mice
if treatment was started within 3 days of the onset of infection. If
treatment with vancomycin was delayed for 7 days or more, vancomycin
failed to eradicate infection with B. burgdorferi or B. turicatae from
immunodeficient mice. The failure of vancomycin in eradicating
established infections in immunodeficient mice was associated with the
persistence of viable spirochetes in the brain during antibiotic
treatment. PMID: 8913478 [PubMed - indexed for MEDLINE]
See the Chronology of the Lyme crimes for the older references
Identify the disease early and treat it aggressively, but always
remember the Trojan Horse, so avoid psychiatry, because they, in their
hysteria and hissy-fitting response to this website and the proofs
that Lyme is a permanent brain infection, dared to say, "There will be
no more spirochete-like discoveries."
To which we reply, "We think it's a free-for-all, now, and anyone
can make up any diseases they want, as long as you psychiatrists claim
to have the magical ability to diagnose us with anything without the
use of any scientifically valid tests."
I say, "RETROCHONDRIA!!" in your general direction.
I say, "The AMA has FLACCITUDE!"
"Your ideas are Steereborn!!"
We say, "Meet me at the Yale Center for the Study of Erections,
and we can have a discussion about all your uncomplicated variables ."
==========================================================================
22) An independent study on spirochetes in the brain from
dentists and they say:
Molecular and immunological evidence of oral Treponema in the
human brain and their association with Alzheimer's disease.
http://www.ncbi.nlm.nih.gov...11929559 medline link to verify
Riviere GR, Riviere KH, Smith KS.
Department of Pediatric Dentistry, School of Dentistry, Oregon
Health and Sciences University, Portland, OR 97201-3097, USA.
The purpose of this investigation was to use molecular and
immunological techniques to determine whether oral Treponema infected
the human brain. Pieces of frontal lobe cortex from 34 subjects were
analyzed with species-specific PCR and monoclonal antibodies. PCR
detected Treponema in 14/16 Alzheimer's disease (AD) and 4/18 non-AD
donors (P < 0.001), and AD specimens had more Treponema species than
controls (P < 0.001). PCR also detected Treponema in trigeminal
ganglia from three AD and two control donors. Cortex from 15/16 AD
subjects and 6/18 controls contained Treponema pectinovorum and/or
Treponema socranskii species-specific antigens (P < 0.01). T.
pectinovorum and/or T. socranskii antigens were also found in
trigeminal ganglia and pons from four embalmed cadavers, and 2/4
cadavers also had Treponema in the hippocampus. These findings suggest
that oral Treponema may infect the brain via branches of the
trigeminal nerve.
PMID: 11929559 [PubMed - indexed for MEDLINE]
"PCR detected Treponema in 14/16 Alzheimer's disease (AD) and 4/18
non-AD donors."
"Cortex from 15/16 AD subjects and 6/18 controls contained
Treponema pectinovorum and/or Treponema socranskii species-specific
antigens."
We wondered why this information never makes breaking headline
news as regards new developments in Alzheimer's but then we remember
the American Psychiatric Association has become like the Pope in his
treatment of Galileo. Such is heresy against the dogma that "no more
spirochete-like discoveries will be made."
Despite the history and syphilis and the insane asylums and
Ehrlich's Compound 606, the arsenic bullet and so on and so forth...
==========================
23) Mousehausen's is now official CDC admits ceftriaxone fails to
eradicate all spirochetes.
http://aac.asm.org/cgi/content/abstract/AAC.01050-07v1
Persistence of Borrelia burgdorferi Following Antibiotic
Treatment in Mice
Emir Hodzic, Sunlian Feng, Kevin Holden, Kimberly J. Freet,
and Stephen W. Barthold*
Center for Comparative Medicine, Schools of Medicine and
Veterinary Medicine, University of California at Davis, One Shields
Avenue, Davis, CA 95616
The effectiveness of antibiotic treatment was examined in a
mouse model of Lyme borreliosis. Mice were treated with ceftriaxone or
saline for one month, commencing during the early (3 weeks) or chronic
(4 months) stages of infection with Borrelia burgdorferi. Tissues from
mice were tested for infection by culture, polymerase chain reaction
(PCR), xenodiagnosis, and transplantation of allografts at 1 and 3
months after completion of treatment. In addition, tissues were
examined for spirochetes by immunohistochemistry. In contrast to
saline-treated mice, mice treated with antibiotic were consistently
culture-negative, but tissues from some of the mice remained PCR-
positive, and spirochetes could be visualized in collagen-rich
tissues. Furthermore, when some of the antibiotic treated mice were
fed upon by Ixodes scapularis ticks (xenodiagnosis), spirochetes were
acquired by the ticks, based upon PCR, and ticks from those cohorts
transmitted spirochetes to naïve SCID mice, which became PCR-positive,
but culture-negative. Results indicated that following antibiotic
treatment, mice remained infected with non-dividing but infectious
spirochetes, particularly when antibiotic treatment was commenced
during the chronic stage of infection.
Ya gonna argue with the CDC, now?
spirochetes were acquired by the ticks
Culture negative means nothing, as we know. It could take
months in vitro. They should have completed the Mouse Infectivity
Test.
=============================
24)
http://www.ncbi.nlm.nih.gov/pubmed/17045505?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
-
CDC on intracellular nerve and brain borrelia spirochetes
We all wonder how the hell the CDC can talk about this phenomenon
and not come right and say "Lyme is a relapsing fever organism and is
incurable due to their intracellularity and the formation of dormant
cyst or spheroplast forms, which are also inhalable," - since this is
all either their own data, or the NIH's data, or the US Army's data.
================================
25) Willy Burgdorfer discussing the cyst or the spheroplast
form. Combine that with the reality that CDC officers discuss
intracellular spirochetes (Mark Klempner and the one above). While
Willy Burgdorfer is discussing European articles, however - disclaimed
as invalid by the CDC except when Allen Steere does it (Chapter 3) -
recall that Willy Burgdorfer was himself recruited by the NIH Rocky
Mountains Bioweapons Lab (which had a moat dug around it hmmm
strangely like a mini island, like a mini Plum Island) from
Switzerland, and the NIH also recruited the German scientist Roland
Martin to head up the NINDS-Multiple Sclerosis group.
So, everyone can discount CDC's discount of foreign research since
obviously no matter what they say, it's a lie.
==================================================
SAY THE IDSA GUIDELINES (GARY WORMSER, et al, or the Original
ALDF.com "entrepreneurial trio" gang of:
"The entrepreneurial trio are Durland Fish, Ph.D.,
former director of the College's Lyme Disease Center and now a
research scientist at Yale; Gary P. Wormser, M.D., still professor of
medicine and pharmacology and chief of the Division of Infectious
Diseases at the College; and John J. Connolly, Ed.D., former College
president and current chairman of the board of the American Lyme
Disease Foundation, Inc., which had its genesis on the Valhalla
campus in 1990."
http://www.journals.uchicago.edu/doi/full/10.1086/508667 ◄ "The
2006 IDSA Guidelines"
"The notion that symptomatic, chronic B. burgdorferi infection
can exist despite recommended
treatment courses of antibiotics (tables 2 and 3) in the
absence of objective clinical signs of
disease, is highly implausible as evidenced by (1) the lack of
antibiotic resistance in this genus
[39, 40, 310], (2) the lack of correlation of persistent
symptoms with laboratory evidence of
inflammation or with the eventual development of objective
physical signs [223, 257, 288, 289],
and (3) the lack of precedent for such a phenomenon in other
spirochetal infections [315-317].
[Lyme is a "STEALTH DISABLER" and as shown in the Yale
Congenital Lyme Autopsy report, there was "NO INFLAMMATION." SEE THE
BIOMARKERS and the MARK KLEMPNER CHAPTER; NOT CAPTURING THEIR OWN
IDENTIFIED BIOMARKERS of disease and instead, deploying the invalid
mumbo-jumbos (psychiatry) is a research fraud crime.]
"Additional compelling evidence against the hypothesis that
persistent symptoms are the result of
persistent infection is the fact that the concentrations of
antibodies against B. burgdorferi in
many of these patients diminish to undetectable levels [257,
286, 288, 318]. The panel is unaware
of any chronic infection in which antibody titers diminish
despite persistence of the causative
organism. [VERY DAMNING statement. This phenomenon is related
to the "stealth disabler" mechanisms of fungal or mycoplasmal or
mycobacterial antigens- no antibodies are made against the infection
due to TLR2 tolerization and the downregulation of HLA or antigen-
presenting molecules Wormser is aware of the immune suppression
aspects of OspA vaccination, since he reported about it:
Gary Wormser reporting the blunting of the immune response
in vaccinated animals:
http://www.ncbi.nlm.nih.gov/pubmed/10865170?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
"OspA interferes with the response of lymphocytes to
proliferative stimuli including a blocking of cell cycle phase
progression."
"In syphilis, patients who are regarded as having treatment
failure typically have persistent or rising titers of antibodies
[319]. [THE IMMUNE SUPPRESSING PlumIsland PAM3CYS LIPOPEPTIDE OSPA IS
NOT FOUND IN TREPONEMA PALLIDUM]
"Finally, Lyme disease lacks characteristics of other
infections that justify longer treatment courses, such as infections
in immunodeficient hosts, [YOU ARE REALLY GONNA BE SHOCKED when you
see the Plum Island Mycoplasmal-immune suppressing data, the
activation of latent viruses data (auto-kill turned off) the HIV
Pam3Cys immune depression data, and the Fungal Vaccines data]
infections in which a pathogen is inhibited but not killed by
antimicrobial therapy or in which available antimicrobials are
minimally active in vitro [JOHNSON CULTURING FROM SPHEROPLAST COULD
TAKE MONTHS], infections caused by an intracellular pathogen
[KLEMPNER- "cef fails"], infections involving a biofilm, infections on
a heart valve, or infections involving a clinical site in which there
is ischemia, a foreign body, a sequestrum***, or frank pus [170]. The
“cystic” forms of B. burgdorferi that have been seen under certain
growth conditions in vitro have not been shown to have any clinical
significance [320]. [INTRACELLULAR CYSTS are the KEY TO LATENCY, well-
known historically, and this is an application of the NEGATIVE DATA
RULE, which is another research fraud crime indictment point; THE
MOUSE INFECTIVITY TEST HAS NOT BEEN PERFORMED ON TREATED MICE OR
MONKEYS]
CDC and NIH Rocky Mountain antibody-gold sphere method
as applied to borreliosis:
The Method Developed:
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=261539&blobtype=pdf
*** Applied to Borreliosis by NIH Rocky Mountain Lab:
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=269963&blobtype=pdf
The Dorward/Garon Gold Test Apparently detects plenty
of shed antigen. And it looks pretty sequestery to me, not to mention
we could never determine sequestery sites in a human unless we had a
lot of brains to biopsy, although the dentists did a pretty good job
detecting oral treponemes sequestering in the brains of Alzheimer's
patients- See Item 23, below.
1975 at an international spirochetal diseases conference
for which Willy Burgdorfer was present; "The ability of the borrelia,
especially tick-borne strains to persist in the brain and in the eye
after treatment with arsenic or with penicillin or even after apparent
cure is well known (1). The persistence of treponemes after treatment
of syphilis is a major area which currently requires additional study
(3,5,10,11)." -Jay Sanford, US Military Hospital, Bethesda, MD
As you can see, Gary Wormser, ad IDSA et al, are trying to
deny everything that Lyme actually is. Lyme is stealth (no antibodies
late in the disease), latent, intracellular, is resistant to
antibiotics (goes into a self-protective spheroplast form upon
exposure to antibiotics which is not an "end stage" as the crooks
claim), it goes into a "dormant" or serum-starved or spheroplast mode
(known to the crooks themselves as a "Trojan Horse"), Lyme belongs to
the class of diseases where there is typically no inflammation. It
does not belong to NIAID or Anthony Fauci's division, but the
parasitic diseases division - but it's not going to belong to either
the CDC or the NIH at all after not too long, because when they're
done being investigated we will find that that NIH and the CDC are the
same as the NEJM "peer-reviewers" - not a one of them isn't interest
conflicted. In fact, we will find out what is the exact relationship
between the CDC and Kaiser or else the NAFTA-eers of Canada and Mexico
will discover it and prosecute it.
At this time I recommend that Russia and China infiltrate
Canadian and Mexican business structures such that when the NAFTA
NationRape of the North American Continent takes place, Russia can
return the favor for the Israeli Oligarchic NationRape Escapade under
Yeltsin.
More of these clear rebuttals below and in the
RICOCHRON.htm page.
Remember, the IDSA keywords: "INFLAMMATION" and "OBJECTIVE
SIGNS" (meaning they are still referring to "Lyme Disease" as the
Dearborn definition of "autoimmune bad knee" as seen in the RICO
graphics), because that later comes in in Congenital Lyme ("lack of
inflammation") and the Biomarkers chapter as regards the description
of the immune suppression outcomes of Lyme, which is the key to all of
their crimes, especially as regards this fungal vaccine, LYMErix or
ImmuLyme, or rOspA and the activation of latent viruses of all kinds.
The crooks' own treatment failure or persistence articles
are below.
The IDSA statement about the cysts or the spheroplasts is
yet another criminal matter, since they all referenced Dave Nelson's
"reversion to intact spirochete form from spheroplast within one
minute of the addition of rabbit blood" report, Russell Johnson said
it could take months in culture for the cyst form to regenerate in
media, and the Mouse Infectivity Test has never been tried as a
treatment efficacy trial, ever, to my knowledge in lab animals. They
cannot make the claim that the cyst form hasn't any clinical
significance, since here we have again the Crooks' Negative Data Rule.
At the present time, there are a whole slew of Russian
scientists now studying these intracellular serum-starvation
("Stringent Response") forms at New York Medical College.
http://iai.asm.org/cgi/reprint/70/6/3061
It's pretty hard to find a cohort nowadays of non-HIV
infected syphilis patients. From the 1989 IDSA reviews chapter on
syphilis, it does not sound at all like syphilis is under control or
even given much concern
The serology of syphilis and borreliosis can hardly be
compared anyway due to the fact that Borrelia infect all kinds of
mammals and undergo great antigenic variation. These IDSA criminals
deny the validity of the Borrelia-specific flagellin assays, when
they're the only valid assays.
Anything Wormser says at all needs to be challenged. It's
quite self-evident that nothing about the seriousness of this disease
will Wormser tolerate as a fact to stand out or rise to the surface or
be memorable. Clearly that attack pattern worked in the past as
regards the Tuskegee Bad Blood experiment and it worked for a while as
regards the abuse of Gulf War Illness Veterans, and it works fine as
long at the Lyme Disease Association's Pat Smith insists her drones do
nothing other than worship Pat Smith and pretend to be Stepford Wives
- as if it were admirable to be a brainless-but-pretty robot. But
here is an era where all of these types of abusive medical criminals'
former barriers have come down.
We all know psychiatry is not a medical practice and that
the entire genre is in an embarrassing shambles of BigPharma pay-offs
and incredibly stupid, self-indicting statements every time they're in
the news. They undid themselves because they went exponentially
overboard with their relationships to BigPharma. The Lyme criminals
can no longer deploy psychiatry as they have in the past. Roy Meadows
was himself a fulcrum for change due to the obvious ridiculousness of
the Munchausen's accusations. Sooner or later it would have happened
that someone mentioned the word science in the context of health, when
talking about children and death.
The survivors of the Munchausen's Terror can take comfort
in the fact that God allowed this horror to occur, like He allowed the
Child Protective Services to happen. God intends to send at least 2/3
of all the humans to hell. If you're a survivor of these Terrors,
you've been chosen to send dozens of people to hell for your
suffering. In your suffering, you are suffering with Christ, and He
is pleased with such people the most.
When Jesus said, "the gates of heaven are narrow," and
that few would make it, He would not be lying, would He?
Anyone who has dealt with the Child Protective Services
has no doubt that it is their personal will to torture parents and
children and that they take great pleasure and derive great
satisfaction in destroying people and causing great suffering You can
see it in their queer, sneering, half-cocked smiles. When you know
the CPS, there is no question in your mind that these entities are
demonic. The vast majority of them are either possessed or are far
along the way towards possession. (The only time a possessed person
acts out is when they are attempting to reject the possession. The
rest are asymptomatic, like the CPS and psychiatrists.)
And given the magnitude of this epidemic of Lyme there
had to be an instance where a tick would bite a real scientist.
Perhaps it only happened once, but it happened. A real scientist is
someone who shouts "BULLSHIT!!," in addition to being highly sensitive
to bullshit's occurrence- which would only happen if said scientist is
also a female. We have no other data on that because none exists, or
else, by definition we would hear about it.
COMPREHENSIVE ARTICLE ON SYPHILIS:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16418521
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1048219&blobtype=pdf
http://www.ourladyswarriors.org/prayer/michael.htm
Saint Michael the Archangel,
defend us in battle.
Be our protection against the wickedness and snares of the devil.
May God rebuke him, we humbly pray;
and do Thou, O Prince of the Heavenly Host -
by the Divine Power of God -
cast into hell, satan and all the evil spirits,
who roam throughout the world seeking the ruin of souls.
Amen.
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