Thank you for your kind words.  If you have any questions about my
model, feel free to ask.

My model explains complex experimental results with surprising ease.
Take the following facts, which appear to represent a paradox:

1. Consumption of soy has been shown to prevent prostate cancer.

2. Dr. Leibowitz reports that the PSA goes up for any of his patients
who consume soy products.

3. Other doctors report no correlation between soy consumption and PSA.

Before completing my model, I assumed that Dr. Leibowitz must be
mistaken.  After finishing my model, however, I realized that:

1. Soy protein binds specifically to ER-beta.  Since both ER-alpha and
ER-beta are needed to form telomeres in prostate cells, soy would
prevent telomere formation and thus prevent prostate cancer.

2. Since bcl-2 prevents apoptosis, you want to have as little bcl-2 as
possible in your prostate cancer cells.  Bcl-2 production is inhibited
by DHT+iAR and by E2+ER-beta.  Since all of Dr. Leibowitz's patients are
on 5AR2 inhibitors, they are dependent on E2+ER-beta to keep bcl-2
levels low.  Soy binds to ER-beta preventing E2 from binding to ER-beta,
resulting in increased bcl-2 production.  Therefore, Dr. Leibowitz's
patients have an increased PSA when eating soy, not because the prostate
cancer is growing faster, but because apoptosis is occuring at a much
lower rate.

3. Since other doctors do not use 5AR2 inhibitors on their patients,
bcl-2 levels are kept low by DHT+iAR even when the soy binds to the
ER-beta.  Therefore, no major change in PSA is observered.

The take home lesson from the above is that everyone on 5AR2 inhibitors
should be avoiding soy, flaxseed, and any other foods which bind
specifically to ER-beta.